- Propylthiouracil, Perchlorate, and Thyroid-Stimulating Hormone Modulate High Concentrations of Iodide Instigated Mitochondrial Superoxide Production in the Thyroids of Metallothionein I/II Knockout Mice
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Duan Q, Wang T, Zhang N, Perera V, Liang X, Abeysekera IR, Yao X
- KMID: 2169710
- Endocrinol Metab.
- 2016 Mar;31(1):174-184.
- doi: 10.3803/EnM.2016.31.1.174
BACKGROUND: Increased oxidative stress has been suggested as one of the underlying mechanisms in iodide excess-induced thyroid disease. Metallothioneins (MTs) are regarded as scavengers of reactive oxygen species (ROS) in... -
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