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First Case in Korea of Group B Streptococcus With Reduced Penicillin Susceptibility Harboring Amino Acid Substitutions in Penicillin-Binding Protein 2X

Yi A, Kim CK, Kimura K, Arakawa Y, Hur M, Yun YM, Moon HW

No abstract available.
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Mechanisms of Acquiring Carbapenem-resistance in Acinetobacter Species

Jeong SH

A rapid dissemination of carbapenem-resistant Acinetobacter spp. represents a significant clinical threat. Production of OXA carbapenemases and metallo-beta- lactamases (MBLs) is the most important mechanism in acquiring carbapenem resistance in...
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Substitutions in Penicillin-Binding Protein 1 in Amoxicillin-Resistant Helicobacter pylori Strains Isolated from Korean Patients

Kim BJ, Kim JG

  • KMID: 1712324
  • Gut Liver.
  • 2013 Nov;7(6):655-660.
BACKGROUND/AIMS: A worldwide increase in amoxicillin resistance in Helicobacter pylori is having an adverse effect on eradication therapy. In this study, we investigated the mechanism of the amoxicillin resistance of...
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Detection of Penicillin-resistant Streptococcus pneumoniae by Polymerase Chain Reaction

Lim SY, Bae SI, Lee CH, Kim KD

  • KMID: 2031018
  • Korean J Clin Pathol.
  • 1999 Oct;19(5):516-512.
BACKGROUND: Resistance to penicillin of Streptococcus pneumoniae in clinical isolates has occurred by the development of altered penicillin-binding proteins (PBPs) that have greatly decreased affinity for antibiotics and has been...
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Antimicrobial Susceptibility of Beta-Lactam Antibiotics on Enterococcus

Song SM, Lee JH, Lee NY

  • KMID: 1892796
  • Korean J Clin Microbiol.
  • 1999 Sep;2(2):194-198.
BACKGROUND: Enterococci exhibit intrinsic resistance or high-level minimum inhibitory concentration (MIC) to beta-lactams than other streptococci. This appears to be due to low affinity of penicillin-binding proteins and rarely production...
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A Comparative Analysis of Monofunctional Biosynthetic Peptidoglycan Transglycosylase (MBPT) from Pathogenic and Non-pathogenic Bacteria

Baker AT, Takahashi , Chandra SB

  • KMID: 2166479
  • Genomics Inform.
  • 2010 Jun;8(2):63-69.
Monofunctional biosynthetic peptidoglycan transglycosylase (MBPT) catalyzes the formation of the glycan chain in bacterial cell walls from peptidoglycan subunits: N-acetylglucosamine (NAG) and acetylmuramic acid (NAM). Bifunctional glycosyltransferases such as the...
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Sequencing Analysis of Penicillin-Binding Protein 2B Gene of Streptococcus pneumoniae Isolated in Korea

Lee CK, Lee DH, Ma KR, Kim YK, Lee KN, Song JW, Song KJ, Suh JT

  • KMID: 2300537
  • Korean J Clin Pathol.
  • 1998 Dec;18(4):591-597.
BACKGROUND: The resistance of Streptococcus pneumoniae to penicillin has been rapidly increasing during the recent three decades. In Korea, we found the incidence of penicillin resistance (PR) to pneumococci was...
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PCR Fingerprinting Analysis of Genes Encoding Penicillin-binding Proteins of Multidrug-resistant Streptococcus pneumoniae Isolated from Korea

Song JH, Yang JW, Jin JH, Kim S, Peck KR, Lee H, Lee NY

  • KMID: 2115872
  • Korean J Infect Dis.
  • 1998 Apr;30(2):117-125.
BACKGROUND: The rate of pneumococcal resistance in Korea has surged up to the world's highest level in a short period. To investigate the genetic relatedness and the spread of resistant...
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Antibiotic Treatment of Methicillin-Resistant Staphylococcus epidermidis(MRSE) Infection

Eom JS, Kim WJ

Staphylococcus epidermidis and other coagulase-negative staphylococci (CNS), often dismissed previously as culture contaminants, are assuming great clinical importance as true pathogens. CNS infections are associated with indwelling foreign bodies and...
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Clinical and Genetic Characteristics of Infection by Penicillin-resistant Streptococcus pneumoniae from Community and Hospital

Cheong HJ, Hwang BY, Park CW, Kim WJ, Kim MJ, Park SC, Lee YH

  • KMID: 2305410
  • Korean J Infect Dis.
  • 2001 Apr;33(2):112-122.
BACKGROUND: During the last three decades, the resistance of S. pneumoniae to penicillin has been rapidly increasing in many parts of the world, especially in Korea. To characterize the clinical...
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Ribotyping of Multidrug-resistant Streptococcus pneumoniae from Korea and Other Countries

Song JH, Yang JW, Jin JH, Peck KR, Kim S, Lee NY

  • KMID: 1548824
  • Korean J Infect Dis.
  • 1997 Nov;29(6):469-476.
BACKGROUND: Recent data from Korea showed that penicillin-resistance in pneumococci was more than 70% with 35% of multidrug-resistance (MDR) among invasive isolates. One of the most important reasons for the...
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Unique alterations in penicillin-binding protein 2B of multidrug-resistant Streptococcus pneumoniae from Korea

Song JH, Yang JW, Jin JH, Kang SJ, Hong HS, Kim SW, Lee H, Kim CK, Peck KR, Kim S, Lee NY

  • KMID: 2147919
  • Korean J Infect Dis.
  • 2000 Apr;32(2):108-114.
BACKGROUND: Pneumococcal resistance became a global issue during the past decades. Korea is reported to be the hottest spot in the world with regard to the prevalence of penicillin and...
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Direct Detection of Methicillin-Resistant Staphylococcus aureus from Blood Cultures Using Three Non-Molecular Methods: PBP2a Latex Agglutination, PBP2a Rapid Immunochromatographic Assay and MRSA-Chromogenic Medium

Hong SB, Son BR, Shin KS

BACKGROUND: This study compared three non-molecular methods for the detection of methicillin-resistance directly from blood cultures containing Staphylococcus aureus: penicillin-binding protein (PBP) 2a latex agglutination (LA), PBP2a immunochromatographic assay (ICA)...
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Evaluation of Various Methods for Detection of Methicillin Resistance Staphylococcus aureus (MRSA)

Lee HS, Lim H

  • KMID: 1559945
  • Korean J Clin Microbiol.
  • 2002 Sep;5(2):105-110.
BACKGROUND: Traditional antimicrobial susceptibility test methods for detection of methicillin resistant Staphylococcus aureus(MRSA) require 24 hours to perform. In addition, accuracies of these methods can be influenced by prevalence of...
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Analysis of Gene Mutations Associated with Antibiotic Resistance in Helicobacter pylori Strains Isolated from Korean Patients

An B, Moon BS, Lim HC, Lee YC, Kim H, Lee G, Kim SH, Park M, Kim JB

BACKGROUND/AIMS: This study aims to identify the gene mutation pattern associated with antibiotic resistance for mainly used antibiotics in Helicobacter pylori strains isolated from Koreans. MATERIALS AND METHODS: Seventy-one H. pylori...
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Interaction of the mec Regulator Genes in Methicillin Resistant Staphylococcus

Choi Y, Lim IS, Shim TS, Lee MK, Park AJ

  • KMID: 2207820
  • J Korean Pediatr Soc.
  • 1998 Sep;41(9):1224-1233.
PURPOSE: Low-affinity penicillin-binding protein PBP 2a encoded by mecA is closely related to methicillin resistance in staphylococci, and the expression of PBP 2a is controlled by regulator elements encoded by...
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Rapid Detection of Methicillin-Resistant Staphylococcus aureus by Multiplex PCR

Moon JY, Lee EJ, Kim YB

  • KMID: 2055000
  • J Bacteriol Virol.
  • 2004 Jun;34(2):91-100.
Staphylococcus aureus continues to be the main cause of surgical site infections. Recently, methicillin-resistant S. aureus (MRSA) has been known to be resistant to many kinds of antibiotics and causes...
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Detection of Methicillin-Resistance of Coagulase-negative Staphylococci

Cho YU, Chae JD, Park HY, Kim MN

  • KMID: 1559946
  • Korean J Clin Microbiol.
  • 2002 Sep;5(2):111-118.
BACKGROUND: Coagulase-negative staphylococci (CNS) has been considered as a major causative agent of nosocomial infections. A prompt and accurate detection of methicillin resistance (MR) in staphylococci is a current issue...
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Synergistic Anti-bacterial Effects of Phellinus baumii Ethyl Acetate Extracts and beta-Lactam Antimicrobial Agents Against Methicillin-Resistant Staphylococcus aureus

Hong SB, Rhee MH, Yun BS, Lim YH, Song HG, Shin KS

BACKGROUND: The development of new drugs or alternative therapies effective against methicillin-resistant Staphylococcus aureus (MRSA) is of great importance, and various natural anti-MRSA products are good candidates for combination therapies....
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Early Screening of Oxacillin-Resistant Staphylococcus aureus and Staphylococcus epidermidis from Blood Culture

Jeong J, Chang CL, Park TS, Lee SH, Kim SR, Jeong SH

The timely detection of blood-borne pathogens is one of the most important functions of the microbiology laboratory. Recently, methicillin-resistant staphylococci have become the most important pathogens seen by the laboratory....
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