- Regulation of Cellular Antiviral Signaling by Modifications of Ubiquitin and Ubiquitin-like Molecules
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Li K, Zhong B
- KMID: 2404889
- Immune Netw.
- 2018 Feb;18(1):e4.
- doi: 10.4110/in.2018.18.e4
The initiation of cellular antiviral signaling depends on host pattern-recognition receptors (PRRs)-mediated recognition of viral nucleic acids that are known as classical pathogen-associated molecular patterns (PAMPs). PRRs recruit adaptor proteins... -
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- Ampelopsis japonica Makino Extract Inhibits the Inflammatory Reaction Induced by Pathogen-Associated Molecular Patterns in Epidermal Keratinocytes
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Choi MR, Choi DK, Kim KD, Kim SJ, Kim DI, Im M, Lee Y, Seo YJ, Kim CD, Lee JH
- KMID: 2164643
- Ann Dermatol.
- 2016 Jun;28(3):352-359.
- doi: 10.5021/ad.2016.28.3.352
BACKGROUND: Keratinocytes are the major cells in epidermis, providing barrier components such as cornified cells through the sophisticated differentiation process. In addition, keratinocytes exerts their role as the defense cells... -
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- NOD-Like Receptors in Infection, Immunity, and Diseases
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Kim YK, Shin JS, Nahm MH
- KMID: 2466346
- Yonsei Med J.
- 2016 Jan;57(1):5-14.
- doi: 10.3349/ymj.2016.57.1.5
Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) are pattern-recognition receptors similar to toll-like receptors (TLRs). While TLRs are transmembrane receptors, NLRs are cytoplasmic receptors that play a crucial role in... -
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- Toll-like Receptor 1/2 Agonist Pam3CSK4 Suppresses Lipopolysaccharide-driven IgG1 Production while Enhancing IgG2a Production by B Cells
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Lee SH, Park SR
- KMID: 2404892
- Immune Netw.
- 2018 Feb;18(1):e10.
- doi: 10.4110/in.2018.18.e10
Interaction between pathogen-associated molecular patterns and pattern recognition receptors triggers innate and adaptive immune responses. Several studies have reported that toll-like receptors (TLRs) are involved in B cell proliferation, differentiation,... -
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- Role of inflammasome activation in development and exacerbation of asthma
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Lee TH, Song HJ, Park CS
- KMID: 2397099
- Asia Pac Allergy.
- 2014 Oct;4(4):187-196.
- doi: 10.5415/apallergy.2014.4.4.187
Human airways contact with pathogen-associated molecular patterns and danger-associated molecular patterns present in many environments. Asthmatic's airways may be more susceptible to these patterns and lead to inflammasome activation; however,... -
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