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A Review of Power and Sample Size Estimation in Genomewide Association Studies

Park AK, Kim H

Power and sample size estimation is one of the crucially important steps in planning a genetic association study to achieve the ultimate goal, identifying candidate genes for disease susceptibility, by...
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Classification of Biological Effect of 1,763 MHz Radiofrequency Radiation Based on Gene Expression Profiles

Im CN, Kim EH, Park AK, Park WY

  • KMID: 2166475
  • Genomics Inform.
  • 2010 Mar;8(1):34-40.
Radiofrequency (RF) radiation might induce the transcription of a certain set of genes as other physical stresses like ionizing radiation and UV. To observe transcriptional changes upon RF radiation, we...
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miR-9 and let-7g enhance the sensitivity to ionizing radiation by suppression of NFkappaB1

Arora H, Qureshi R, Jin S, Park AK, Park WY

The activation of nuclear factor-kappa B1 (NFkappaB1) in cancer cells may confer resistance to ionizing radiation (IR). To enhance the therapeutic efficiency of IR in lung cancer, we screened for...
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Genome-wide Response of Normal WI-38 Human Fibroblast Cells to 1,763 MHz Radiofrequency Radiation

Im CN, Kim EH, Park AK, Park WY

  • KMID: 2166474
  • Genomics Inform.
  • 2010 Mar;8(1):28-33.
Increased exposure of human to RF fields has raised concerns for its potential adverse effects on our health. To address the biological effects of RF radiation, we used genome wide...
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Results of contact tracing for SARS-CoV-2 Omicron sub-lineages (BA.4, BA.5, BA.2.75) and the household secondary attack risk

Yu M, Lee SE, Lee HY, Kim Hj, Song YJ, Jeong J, Park AK, Kim IH, Kim Ej, Park YJ

Objectives: This study aimed to assess the contact tracing outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sub-lineages BA.4, BA.5, and BA.2.75 within Republic of Korea, and to...
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The Impact of Entry Restrictions on the Spread of Severe Acute Respiratory Syndrome Coronavirus Variants Between 2021 and 2022

Hong J, Park AK, Radnaabaatar M, Kim EJ, Kim DW, Jung J

To contain the surge of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the South Korean government has implemented non-pharmacological interventions as well as border restrictions. The efficacy of entry restrictions...
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Genomic Surveillance of SARS-CoV-2: Distribution of Clades in the Republic of Korea in 2020

Park AK, Kim IH, Kim J, Kim JM, Kim HM, Lee Cy, Han MG, Rhie GE, Kwon D, Nam JG, Park YJ, Gwack J, Lee NJ, Woo S, No JS, Lee J, Ha J, Rhee J, Yoo CK, Kim EJ

Since a novel beta-coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in December 2019, there has been a rapid global spread of the virus. Genomic surveillance was...
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Overexpression of Mucin 13 due to Promoter Methylation Promotes Aggressive Behavior in Ovarian Cancer Cells

Sung HY, Park AK, Ju W, Ahn JH

PURPOSE: Recent discoveries suggest that aberrant DNA methylation provides cancer cells with advanced metastatic properties. However, the precise regulatory mechanisms controlling metastasis genes and their role in metastatic transformation are...
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Aberrant Promoter Hypomethylation of Sortilin 1: A Moyamoya Disease Biomarker

Sung HY, Lee JY, Park AK, Moon YJ, Jo I, Park EM, Wang KC, Phi JH, Ahn JH, Kim SK

BACKGROUND AND PURPOSE: The pathogenesis of moyamoya disease (MMD) remains poorly understood, and no reliable molecular biomarkers for MMD have been identified to date. The present study aimed to identify...
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Aberrant Hypomethylation of Solute Carrier Family 6 Member 12 Promoter Induces Metastasis of Ovarian Cancer

Sung HY, Yang SD, Park AK, Ju W, Ahn JH

PURPOSE: Ovarian cancer (OC) is the most fatal of gynecological malignancies with a high rate of recurrence. We aimed to evaluate the expression of solute carrier family 6, member 12...
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