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Artifactual Hyperbilirubinemia due to Paraprotein Interference in a Case of Multiple Myeloma

Jang JY, Kim H, Uh Y, Kim J, Yoon KJ, Kim MY, Kong JH

  • KMID: 2200495
  • J Lab Med Qual Assur.
  • 2013 Dec;35(2):133-137.
When analyzing samples containing paraproteins, various interference effects are encountered in the clinical laboratory. Precipitation of paraproteins mostly interferes with the assays that use photometric detection. Herein, we present a...
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A Case of Papular Mucinosis

Song IM, Ihm CW

  • KMID: 2116014
  • Korean J Dermatol.
  • 1997 Oct;35(5):984-988.
Papular mucinosis, also known as lichen myxedematosus or scleromyxedema, is a chronic cutaneous disorder characterizecl by infiltration of mucin in the dermis without abnormalities of thyroid function. It often combines...
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Pseudohyperphosphatemia in a Patient with Multiple Myeloma

Lee Y, Koo T, Yi JH, Choi JH, Han SW, Park IK, Kim HJ

Hyperphosphatemia is an unusual manifestation in patients with multiple myeloma without a significantly reduced glomerular filtration rate. Serum phosphate may be falsely elevated when a large amount of paraproteins is...
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Paraproteinemic neuropathy

Pyun SY, Kim BJ

Paraproteinemia is caused by a proliferation of monoclonal plasma cells or B lymphocytes. Approximately 10% of idiopathic neuropathies are associated with paraproteinemia, where a certain paraprotein acts like an antibody...
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Platelet Dysfunction in a Patient with Multiple Myeloma: A Case Report with a Literature Review

Na SY, Park JW, Choi JS, Lee DH, Chi HS, Lee JS, Suh C

  • KMID: 2264797
  • Korean J Med.
  • 2012 Dec;83(6):823-827.
Multiple myeloma is a monoclonal plasma cell proliferation disorder with various symptoms and signs caused by paraproteinemias. Among these signs, a bleeding tendency is one of the major fatal causes....
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A Case of Non-secretory Plasma Cell Leukemia with Complex Chromosomal Abnormalities

Lee KA, Kwon OG, Oh KJ, Yoon KJ, Lee JI

  • KMID: 1849151
  • Korean J Hematol.
  • 1998 Oct;33(3):449-453.
We report a case of non-secretory plasma cell leukemia with complex chromosomal abnormalities including t (11;14)(q13;q32). A 57-year-old man was admitted to hospital due to anemia, thrombocytopenia and renal insufficiency....
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Two Cases of Papular Mucinosis

Jang JW, Kwon SB, Kim DW, Jun JB, Chung SL

  • KMID: 2303221
  • Korean J Dermatol.
  • 2000 Aug;38(8):1099-1105.
Scleromyxedema is a rare fibromucinous disorder that is often difficult to treat and is associated with significant morbidity and mortality. Clinically, it shows white or flesh colored, dome-shaped waxy papules...
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Crystalline podocytopathy and tubulopathy without overt glomerular proteinuria in a patient with multiple myeloma

Lee EJ, Lee SY, Park SY, Kim Y, Choi JS, Kim MJ, Park JH, Lee JE, Kwon GY, Kim YG

Crystalline nephropathy is a rare yet well-known condition associated with multiple myeloma and other light chain–secreting disorders. Paraproteins that are resistant to proteolysis crystallize within proximal tubular cells and cause...
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A case of multiple myeloma with ascites

Song DS, Han JY, Kwen HJ, Min KO, Lee SS, Kim HS, Seo EJ, Lee KS, Kim MH, Lee EH

  • KMID: 1927582
  • Korean J Med.
  • 2000 Jun;58(6):686-691.
Ascites is a rare complication of multiple myeloma. When it develops, it is usually associated with extensive liver infiltration with plasma cells, infectious peritonitis or myelomatous peritoneal infiltration. Ascites caused by peritoneal infiltration...
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Association between left ventricular function and paraprotein type in patients with multiple myeloma

Yi JE, Lee SE, Jung HO, Min CK, Youn HJ

BACKGROUND/AIMS: Multiple myeloma (MM)–associated cardiac damage, particularly according to the type of monoclonal (M) protein has not been elucidated. We sought to investigate relationship between elevated serum M protein levels...
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Intensely Pruritic Papules and Plaques in Waldenstrom's Macroglobulinemia

Lee S, Lee NR, Choe SJ, Kim BJ, Eom M, Choi EH

Waldenstrom's macroglobulinemia (WM) is lymphoplasmacytoid malignancy that affects B lymphocytes. Cutaneous involvement of WM is rare, but various cutaneous manifestations have been reported. These findings are due to various pathological...
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Clinical Significance of Serum Osteopontin in Patients with Multiple Myeloma

Kang SY, Lee JJ, Lee WI

BACKGROUND: Angiogenesis and osteoclastogenesis are increased in the bone marrow of multiple myeloma (MM) patients in parallel with the tumor progression. Osteopontin (OPN) is a multifunctional protein that is...
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