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Levels of Serum Soluble P-Selectin and E-Selectin in Psoriatic Patients

Ataseven A, Ataseven H, Ozturk P, Ozdemir M, Kesli R

No abstract available.
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Soluble P-selectin, E-selectin, and VCAM-1 as Markers of Vascular Endothelial Damage in Diabetic Patients with Microangiopathy

Kim YS, Byun DW, Seo KI, Yoo MH, Kim GB, Koong SS

  • KMID: 2331646
  • J Korean Diabetes Assoc.
  • 1998 Mar;22(1):35-46.
BACKGROUND: Vascular complications of diabetic patients are common and are known as the major cause of death. Hyperglycemia has been supposed to be the leading cause of vascular complications by...
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Selectins: functional importance as cell adhesion molecule in immune system

Noh Y, Cho D, Ko H, Lim D, Chai HH

Selectins are cell membrane glycoproteins that recognize specific glycoconjugates expressed on the surface of cells. Then, selectins adjust cell-cell interactions that are important in inflammation, hemostasis and cancer metastasis. Selectins...
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Elevated Levels of Soluble E-selectin and P-selectin in Patients with NIDDM

Yoo SD, Kim IJ, Kim YK

  • KMID: 2331645
  • J Korean Diabetes Assoc.
  • 1998 Mar;22(1):23-34.
BACKGROUND: Although there is wide spread agreement that patients with NIDDM are at increased risk of the premature development of atherosclerosis, it is not totally clear why this is so....
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Platelet Activation During Hemodialysis Measured Through Expression of P-selectin

Kim HJ, Koo JR, Chae DW, Noh JW

  • KMID: 2254972
  • Korean J Nephrol.
  • 1998 May;17(3):461-465.
Recent studies suggested that platelet activation with surface expression of P-selectin may be related to a loss of viability and early clearing from circulation by monocytes and macrophages of the...
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The Change of PAC-1 and P-selectin Expression after Initiation of Antiplatelets in Patients with Acute Ischemic Stroke

Park SA, Kim EY, Ha SR, Park JH, Lee TK, Sung KB, Park CS

  • KMID: 1572449
  • J Korean Neurol Assoc.
  • 2006 Jun;24(3):210-214.
BACKGROUND: The purpose of this study was to evaluate the time course of PAC-1 and the P-selectin expression after the initiation of antiplatelets in acute ischemic stroke. METHODS: We serially...
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The Serum Level of Soluble Adhesion Molecules in Patients with Acute Ischemic Stroke

Cha JK, Kim SH, Kim JW, Jeong MH

  • KMID: 2016299
  • J Korean Neurol Assoc.
  • 1998 Dec;16(6):788-793.
BACKGROUNDS: Recent experimental studies demonstrate massive leukocytes extravasation at sites of cerebral ischemia even with the first hours of disease. Leukocytes are now considered to potentiate ischemic neural damage by...
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Increased Serum Level of P-Selectin in Patients with Lichen Planus

Erdem T, Gulec AI, Aktas A, Yildirim A, Kiziltunc

  • KMID: 2428315
  • Yonsei Med J.
  • 2004 Apr;45(2):215-218.
Lichen planus (LP) is a common, pruritic and inflammatory disease of the skin, hair follicles and mucous membranes. Immunologic mechanisms, especially cell-mediated immunity, play a major role in triggering the...
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Plasma Levels of Soluble Adhesion Molecules in Patients with Acute Cerebral Ischemic Stroke

Yu SW, Park MK, Park KW, Lee DH

  • KMID: 2338253
  • J Korean Geriatr Soc.
  • 2003 Jun;7(2):146-153.
BACKGROUNDS: The inflammatory reaction after cerebral ischemia involving adhesion molecules aggravates neurologic deficit. This study aimed to study the change of plasma level of the adhesion molecules after acute cerebral...
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Glycobiology of Selectin

Kim YS, Ko JH

Selectins, carbohydrate-binding molecules, bind to fucosylated and sialylated glycoprotein ligands, and are found on endothelial cells, leukocytes and platelets. They can be classified into E-, L- and P-selectins, and are...
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Effect of High Glucose Concentration on Expression of Adhesion Molecules in Endothelial Cells

Kim IJ, Son SM, Lee MK, Jeong H, Kim YK

  • KMID: 2331670
  • J Korean Diabetes Assoc.
  • 1998 Sep;22(3):280-289.
BACKGROUND: Accelerated atherosclerotic vascular disease is the leading cause of mortality in patients with diabetes mellitus. Endothelial dysfunction, monocytes, and platelets are well known pathogenic factors in atherogenesis. Changes in...
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Expression of Adhesion Molecules in IgA Nephropathy, Diffuse Crescentic Glomerulonephritis, and Minimal Change Disease

Moon KC, Park SY, Kim HW, Lee HS

  • KMID: 2275654
  • Korean J Pathol.
  • 2000 May;34(5):331-340.
Accumulation of leukocytes within the glomerulus is a key event in the pathogenesis of glomerulonephritis. This process is mediated by pairs of adhesion molecules. We have examined the expression pattern...
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The relationship between serum adiponectin and inflammatory cytokines in obese Korean juveniles

Byun SH, Kwon EB, Kim SY

PURPOSE: Obesity is related to systemic inflammatory processes causing cardiovascular complications. Intercellular adhesion molecule-1 (ICAM-1), CD40 ligand (CD40L), P-selectin are newly described mediators of inflammation and have a significant effect...
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Expression of P-selectin mRNA and Protein on Hypoxic-Ischemic Brain Injury in Neonatal Rat

Kim KB, Lim JH, Pee DH, Eun BL, Tockgo YC

  • KMID: 2137162
  • J Korean Child Neurol Soc.
  • 2001 May;9(1):59-68.
PURPOSE: The selectin family of adhesion molecules plays a role in the initiation of endothelium-leukocyte interaction of inflammation and ischemia-reperfusion. P-selectin, a rapidly expressed endothelial cell adhesion molecule, is essential...
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Surface Expression of P-selectin on Platelets Is Related with Clinical Worsening in Acute Ischemic Stroke

Cha JK, Jeong MH, Kim EK, Lim YJ, Ha BR, Kim SH, Kim JW

Platelet activation has a critical role in arterial disorders. In this study, we showed that the upregulation of P-selectin expression on platelets was related with clinical worsening in acute...
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Vibrio vulnificus cytolysin induces hyperadhesiveness of pulmonary endothelial cells for neutrophils through endothelial P-selectin: a mechanism for pulmonary damage by Vibrio vulnificus cytolysin

Kim BS, Kim JS

  • KMID: 931882
  • Exp Mol Med.
  • 2002 Sep;34(4):308-312.
Vibrio vulnificus cytolysin forms transmembrane pores that are permeable to calcium ions in pulmonary endothelial cells, and has been suggested as an important virulence factor that sequestrate neutrophils primarily...
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The Inhibitory Effect of Anti-P-Selectin, Anti-PSGL-1 and Anti-CD49d Antibodies on Experimental Allergic Airway Inflammation in Mice

Park SW, Kim AY, Jin YD, Koo BS, Kim YM, Park YH, Park CI, Rha KS

  • KMID: 2297692
  • J Rhinol.
  • 2005 May;12(1):32-38.
BACKGROUND AND OBJECTIVES: Eosinophil recruitment in allergic inflammation is dependent on the interactions between adhesion molecules. The objective of this study was to determine whether blocking of P-selectin glycoprotein ligand-1...
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Enhanced Expression of Cell Adhesion Molecules in the Aorta of Diabetic Mice is Mediated by gp91phox-derived Superoxide

Yun MR, Kim JJ, Lee SM, Heo HJ, Bae SS, Kim CD

  • KMID: 2285317
  • Korean J Physiol Pharmacol.
  • 2005 Apr;9(2):109-115.
Endothelial activation and subsequent recruitment of inflammatory cells are important steps in atherogenesis. The increased levels of cell adhesion molecules (CAM) have been identified in diabetic vasculatures, but the underlying...
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Inhibition of expression of P-selectin by antioxidant in cholesterol-fed rats

Lee CS, Choi JM, Park DH, Kang DY, Register T, Adams MR

Butylated hydroxytoluene (BHT) can inhibit experimental atherosclerosis in animals. Although the agent is an antioxidant, the exact mechanism of the reaction in atherosclerosis is still unknown. To investigate the effects...
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Effects of Cilostazol on Platelet Activation in Coronary Stenting Patients Who Already Treated with Aspirin and Clopidogrel

Ahn JC, Song WH, Kwon JA, Park CG, Seo HS, Oh DJ, Rho YM

  • KMID: 1109521
  • Korean J Intern Med.
  • 2004 Dec;19(4):230-236.
BACKGROUND: A recent study has shown that triple anti-platelet therapy (cilostazol+clopidogrel+aspirin) resulted in a significantly lower restenosis rate after coronary stenting than did conventional therapy (clopidogrel+aspirin). However, the anti-platelet effects...
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