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Glycogen Synthase Kinase 3 Inactivation Induces Cell Senescence through Sterol Regulatory Element Binding Protein 1-Mediated Lipogenesis in Chang Cells

Kim YM, Song I, Seo YH, Yoon G

BACKGROUND: Enhanced lipogenesis plays a critical role in cell senescence via induction of expression of the mature form of sterol regulatory element binding protein 1 (SREBP1), which contributes to an...
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Characterization of cis-acting elements in the rat ATP citrate-lyase gene promoter

Moon YA, Park SW, Kim KS

  • KMID: 1093599
  • Exp Mol Med.
  • 2002 Mar;34(1):60-68.
The cis-acting element in the promoter of the rat ATP-citrate lyase (ACL) and transcription factors which interact with these elements were determined. Six Sp1 binding sites and CAAT box exist...
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