- Neurotoxicity Screening in a Multipotent Neural Stem Cell Line Established from the Mouse Brain
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Choi YS, Lee MC, Kim HS, Lee KH, Park YG, Kim HK, Jeong HS, Kim MK, Woo YJ, Kim SU, Ryu JK, Choi HB
- KMID: 1778041
- J Korean Med Sci.
- 2010 Mar;25(3):440-448.
- doi: 10.3346/jkms.2010.25.3.440
Neural stem cells (NSCs) have mainly been applied to neurodegeneration in some medically intractable neurologic diseases. In this study, we established a novel NSC line and investigated the cytotoxic responses... -
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- Reduced dihydroxyacetone sensitivity and normal sensitivity to glyceraldehyde and oxidizing agent of ATP-sensitive K+ channels of pancreatic beta cells in NIDDM rats
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Song DK, Park WK, Bae JH, Park MK, Kim SJ, Ho WK, Earm YE
- KMID: 1081048
- J Korean Med Sci.
- 1997 Aug;12(4):286-292.
- doi: 10.3346/jkms.1997.12.4.286
The inhibition of ATP-sensitive K+(KATP) channels in pancreatic beta cells is a key step of insulin secretion induced by glucose. Glucose-induced insulin secretion from the beta cells is selectively... -
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- Regulation of bcl-2 family in hydrogen peroxide-induced apoptosis in human leukemia HL-60 cells
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Lee JE, Sohn JW, Lee JH, Lee KC, Son CS, Tockgo YC
- KMID: 927133
- Exp Mol Med.
- 2000 Mar;32(1):42-46.
Numerous types of cells have been shown to undergo apoptosis when exposed to oxidant agent such as hydrogen peroxide. In order to understand the functional relationship between the anti- and... -
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- Dual effect of oxidative stress on NF-kappaB activation in HeLa cells
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Byun MS, Jeon KI, Choi JW, Shim JY, Jue DM
- KMID: 755204
- Exp Mol Med.
- 2002 Nov;34(5):332-339.
Reactive oxygen species (ROS) has been implicated as an inducer of NF-kappaB activity in numbers of cell types where exposure of cells to ROS such as H2O2 leads to NF-kappaB... -
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- Down syndrome critical region 1 enhances the proteolytic cleavage of calcineurin
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Lee JE, Jang H, Cho EJ, Youn HD
- KMID: 1058021
- Exp Mol Med.
- 2009 Jul;41(7):471-477.
- doi: 10.3858/emm.2009.41.7.052
Down syndrome critical region 1 (DSCR1), an oxidative stress-response gene, interacts with calcineurin and represses its phosphatase activity. Recently it was shown that hydrogen peroxide inactivates calcineurin by proteolytic cleavage.... -
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- Sulfhydryl modification affects coronary artery tension by changing activity of delayed rectifier K+ current
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Ha M, Kwon S, Lee YH, Yeon D, Ahn DS
- KMID: 711760
- Yonsei Med J.
- 2000 Jun;41(3):372-380.
- doi: 10.3349/ymj.2000.41.3.372
It has been reported that a change in the cellular redox state may be involved in the regulation of vascular tone, but the underlying mechanism is not fully understood. The... -
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