- The Challenge of Designing Stroke Trials That Change Practice: MCID vs. Sample Size and Pragmatism
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Goyal M, McDonough R, Fisher M, Ospel J
- KMID: 2525330
- J Stroke.
- 2022 Jan;24(1):49-56.
- doi: 10.5853/jos.2021.02740
Randomized controlled trials (RCT) are the basis for evidence-based acute stroke care. For an RCT to change practice, its results have to be statistically significant and clinically meaningful. While methods... -
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- Sex and Gender Differences in Stroke and Their Practical Implications in Acute Care
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Ospel J, Singh N, Ganesh A, Goyal M
- KMID: 2539055
- J Stroke.
- 2023 Jan;25(1):16-25.
- doi: 10.5853/jos.2022.04077
There are several controversies regarding the role of sex and gender in the pathophysiology and management of acute stroke. Assessing the role of sex, i.e., biological/pathophysiological factors, and gender, i.e.,... -
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