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Effects of Increased Uric Acid Intake on the Abundance of Urate-anion exchanger and Organic Anion Transporter Proteins in the Rat Kidney

Kim S, Lee CH, Kang CM, Kim GH

Renal handling of uric acid mainly occurs in the proximal tubule, and bidirectional transport of urate may involve apical absorption via the urate-anion exchanger (URAT1) and basolateral uptake via organic...
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Effects of Losartan Administration on Uric acid Transporters in Rat Kidney

Kim S, Lee CH, Kang CM, Kim GH

  • KMID: 2012309
  • J Korean Soc Hypertens.
  • 2010 Jun;16(2):19-27.
BACKGROUND: Losartan, an angiotensin II receptor blockade, has been reported to decrease the serum uric acid level through its uricosuric action. However, the mechanism by which losartan affects renal handling...
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Co-localization and interaction of organic anion transporter 1 with caveolin-2 in rat kidney

Kwak JO, Kim HW, Oh KJ, Kim DS, Han KO, Cha SH

  • KMID: 1056233
  • Exp Mol Med.
  • 2005 Jun;37(3):204-212.
The organic anion transporters (OAT) have recently been identified. Although the some transport properties of OATs in the kidney have been verified, the regulatory mechanisms for OAT's functions are still...
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