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Histopathological Changes of Olfactory Epithelium in the Rats Exposed to Cigarette Smoke

Koo HJ, Lee HS, Cho KS, Park HY, Roh HJ

  • KMID: 1875403
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2007 Sep;50(9):766-772.
BACKGROUND AND OBJECTIVES: Although exposure to cigarette smoke has been reported to be associated with olfactory dysfunction, the pathophysiology is poorly understood. The purpose of this study is to evaluate...
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Effect of Systemic Steroid on the Olfactory Epithelium Injured by 3-Methylindole in Mice

Park HT, Kim YM, Rha KS

  • KMID: 2297634
  • J Rhinol.
  • 2009 Nov;16(2):99-104.
BACKGROUND AND OBJECTIVES: Various chemicals can affect the function of olfaction and steroids have been used for the treatment of olfactory dysfunction. In this study, we investigated the effect of...
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The Effect of Topical Steroid Nasal Instillation in Induced Anosmic Mice

Kim BG, Park SY, Jung DG, Cho JH, Lee DM, Kim MW

  • KMID: 2276301
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Dec;47(12):1256-1260.
BACKGROUND AND OBJECTIVES: The purpose of this study was to evaluate the effect of intranasal Mometasone furoate instillation into the nasal cavity of mice which had peripherally induced anosmia. SUBJECTS...
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Transplantation of Neural Stem Cells in Anosmic Mice

Lee CH, Jeon SW, Seo BS, Mo JH, Jeon EH, Choi AR, Kim JW

OBJECTIVES: Treating olfactory dysfunction is a challenge for physicians. One of the therapeutic options could be transplantation of stem cells. In this study, neural stem cells were transplanted into anosmic...
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Immunohistological Study of the Effects of Intranasal ZnSO4 Instillation on the Mouse Olfactory Epithelium and Olfactory Bulb

Kim MW, Moon YW, Kim BG, Kwak BK, Park YJ

  • KMID: 2276620
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 Apr;49(4):395-401.
BACKGROUND AND OBJECTIVES: The purpose of this study was to evaluate the time course of functional and anatomical recovery of the olfactory epithelium (OE) and olfactory bulb (OB) following intranasal...
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Reversal of Olfactory Disturbance in Allergic Rhinitis Related to OMP Suppression by Intranasal Budesonide Treatment

Jung AY, Kim YH

PURPOSE: We evaluated the severity of olfactory disturbance (OD) in the murine model of allergic rhinitis (AR) and local allergic rhinitis (LAR) in mice. We also investigated the therapeutic effect...
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Gene Expression Profile of Olfactory Transduction Signaling in an Animal Model of Human Multiple Sclerosis

Kim J, Ahn M, Choi Y, Ekanayake , Park CM, Moon C, Jung K, Tanaka A, Matsuda H, Shin T

Olfactory dysfunction occurs in multiple sclerosis in humans, as well as in an animal model of experimental autoimmune encephalomyelitis (EAE). The aim of this study was to analyze differentially expressed...
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The Effect of Superior Cervical Ganglionectomy on Recovery of Olfaction in Induced Anosmic Mice

Lee NS, Kim BG, Park JM, Park YS, Kim SW, Kim SW, Lee SK

  • KMID: 2115494
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Dec;48(12):1462-1467.
BACKGROUND AND OBJECTIVES: This study was undertaken to evaluate the effect of superior cervical ganglionectomy (SCG) on anosmia, which is peripherally induced in the mice. MATERIALS AND METHOD: Three groups...
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