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Effect of Ginseng Saponins on Nicotine-Induced Dopamine Release in the Rat Nucleus Accumbens and Striatum

Kim SE, Shim I, Chung JK, Lee MC

  • KMID: 1613906
  • Korean J Nucl Med.
  • 2002 Oct;36(5):277-287.
No abstract available.
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Effect of Pretreatment of (-)-3-PPP on the Haloperidol-Induced Extracellular Dopamine Concentraions in the Nucleus Accumbens of Rats

Chung YC, Eun HB, Hwang IK, Park TW

  • KMID: 2142162
  • J Korean Soc Biol Psychiatry.
  • 2001 Jun;8(1):79-84.
OBJECTIVES: To investigate the effects of (-)-3-PPP(0.5, 2, and 10mg/kg, s.c.) and haloperidol(0.1, 0.5, and 2mg/kg, s.c.) on the extracellular dopamine concentrations, and the effect of pretreatment with (-)-3-PPP(2mg/kg) on...
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Cocaine-Induced Behavioral Sensitization in Mice: Effects of Microinjection of Dopamine D2 Receptor Antagonist into the Nucleus Accumbens

Jung ES, Lee HJ, Sim HR, Baik JH

To determine the role of dopamine D2 receptor (D2R) in the nucleus accumbens (NAc) core in cocaine-induced behavioral sensitization, D2R antagonist, raclopride was bilaterally microinjected (2.5 or 5 nmol) into...
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Ultrastructure of Fronto-Accumbens Synapses after Prefrontal Decortication of the Rat

Song HG, Ahn ET, Ko JS, Park KH

  • KMID: 2092810
  • Korean J Anat.
  • 2003 Oct;36(5):405-416.
Prefrontal cortex is called psycological cortex, since it deals with making up of individual personality, regulation of personal depth of feeling, working memory, planning, maintaining attention, etc. Whereas, nucleus accumbens...
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Effect of Ritanserin on the Circling Movement in the Unilateral Substantia Nigra-Lesioned Rats

Kim IH, Chung YC, Eun HB

  • KMID: 1554198
  • Korean J Psychopharmacol.
  • 1999 Oct;10(2):130-137.
OBJECTIVE: Recently, the serotonin-dopamine interaction is being regarded as a possible mechanism for both less extrapyramidal symptoms and good therapeutic effect on negative symptoms which are outstanding advantages of atypical...
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Organization of Direct Hippocampal Projections to the Different Regions of the Ventral Striatum in primate

Jung Y, Hong S, Haber SN

  • KMID: 1894519
  • Korean J Anat.
  • 2003 Feb;36(1):67-76.
The organization of the striatal projection fibers from the hippocampal formation (HF) was studied in the monkey with particular emphasis on specific projections of the ventral striatum. Retrograde tracers were injected...
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Effects of Coadministraion of (-)-3-PPP and Haloperidol on the c-fos Expression in the Nucleus Accumbens and Prefrontal Cortex of Rats

Park KH, Chung YC, Eun HB, Park TW

  • KMID: 1607281
  • Korean J Psychopharmacol.
  • 2001 Jun;12(2):133-139.
OBJECTIVE: The purpose of our study was to measure and compare the c-fos mRNA expression patterns in the nucleus accumbens (NAS) and prefrontal cortex (PFC) of rats after the administration...
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Temporal Pole Projections to the Ventral Shell Striatal Subterritory in the Primate

Jung Y

  • KMID: 1610760
  • Korean J Anat.
  • 2003 Aug;36(4):265-270.
Paralimbic association area in the temporal pole is situated between sensory association areas and the limbic regions and has direct connections with these areas and the ventral striatum. Corticostriatal connections...
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Distribution of the Mouse Striatal Cholinergic Neurons in Their Early Postnatal Period

Hann HJ, Lee HL

  • KMID: 2092652
  • Korean J Anat.
  • 1998 Aug;31(4):503-511.
The category of striatal complex contains caudate nucleus, putamen, nucleus accumbens septi, and olfactory tubercle. The striatal complex is composed of two compartments, dorsal and ventral striatum. In the striatum,...
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Blockade of ERK Phosphorylation in the Nucleus Accumbens Inhibits the Expression of Cocaine-induced Behavioral Sensitization in Rats

Kim S, Shin JK, Yoon HS, Kim JH

Repeated administration of psychostimulants such as cocaine leads to the development of behavioral sensitization. Extracellular signal-Regulated Kinase (ERK), an enzyme important for long-term neuronal plasticity, has been implicated in such...
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Comparison of sucrose and ethanol-induced c-Fos-like immunoreactivity in the parabrachial nuclei and accumbens nucleus

Kim Y, Cho YK

Sucrose and alcohol are rewarding and appetitive. They are occasionally over-consumed and cause addiction. The parabrachial nuclei (PbN) are the second taste relay in the central taste pathway. The nucleus...
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Ezrin-radixin-moesin proteins are regulated by Akt-GSK3β signaling in the rat nucleus accumbens core

Kim WY, Cai WT, Jang JK, Kim JH

The ezrin-radixin-moesin (ERM) proteins are a family of membrane-associated proteins known to play roles in cell-shape determination as well as in signaling pathways. We have previously shown that amphetamine decreases...
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The Effect of Immobilization Stress and Corticosterone on Haloperidol-induced c-fos Expression in Rat Brain

Yoon JH, Kim KS, Lee KU, Lew TY

  • KMID: 2037062
  • Korean J Psychopharmacol.
  • 2002 Dec;13(4):269-275.
OBJECTIVE: Immediate early gene (IEG), c-fos is known to encode a 62 kDa nuclear protein (Fos) which has a critical role in the stimulus response process of many cells. c-fos...
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A Group of Descending Glutamatergic Neurons Activated by Stress in Corticolimbic Regions Project to the Nucleus Accumbens

Park JY, Park SY, Kwon H, Song Y, Yun B, Lee Y, Cho Y, Joo A, Han PL

The nucleus accumbens (NAc) is the major component of the ventral striatum that regulates stress-induced depression. The NAc receives dopaminergic inputs from the ventral tegmental area (VTA), and the role...
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Experience of Neonatal Maternal Separation May Lead to a Long-term Modulation in the Neuronal Activity of Nucleus Accumbens in the Offspring

Ryu V, Yoo SB, Kim BT, Lee JH, Jahng JW

Dysfunction of the nucleus accumbens (NAcb) is implicated in the development of anhedonia, a core symptom of major depressive disorder. In order to define the neural basis of depression-like behaviors...
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Neurobiology of Depression

Kim YK

Depression is a heterogeneous group of syndromes comprised of numerous diseases of distinct causes and pathophysiologies. Recently, several promising hypotheses of depression and antidepressant action have been formulated. These hypotheses...
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Neurotoxicity of Synthetic Cannabinoids JWH-081 and JWH-210

Cha HJ, Seong YH, Song MJ, Jeong HS, Shin J, Yun J, Han K, Kim YH, Kang H, Kim HS

Synthetic cannabinoids JWH-018 and JWH-250 in 'herbal incense' also called 'spice' were first introduced in many countries. Numerous synthetic cannabinoids with similar chemical structures emerged simultaneously and suddenly. Currently there...
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The Role of PKMzeta in Drug Reward Memory

Song MJ, Kim JH

  • KMID: 2287495
  • Korean J Psychopharmacol.
  • 2012 Jul;23(3):83-87.
Drug addiction is a chronic brain disease with a high incidence of relapse. Environmental cues that previously and repeatedly associated with drugs of abuse easily evoke relapse to addicts even...
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Functional Connectivity of Basolateral Amygdala Neurons Carrying Orexin Receptors and Melanin-concentrating Hormone Receptors in Regulating Sociability and Mood-related Behaviors

Kim TK, Han PL

Chronic stress induces changes in neuronal functions in specific brain regions regulating sociability and mood-related behaviors. Recently we reported that stress-induced persistent upregulation of the neuropeptides orexin and melanin-concentrating hormone...
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An Autoradiographic Study on the Rat Neostriatal Dopamine Receptor Changes after 6-hydroxydopamine Injection into the Medial Prefrontal Cortex

Kwon JS, Lee DY, Woo JI

  • KMID: 2340296
  • J Korean Neuropsychiatr Assoc.
  • 1999 Mar;38(2):408-418.
The frontal cortex of rat is innervated by dopaminergic pathway(mesocortical pathway) arising from ventral tegmental area. Several studies have suggested that mesocortical dopaminergic neurons may modulate the function of dopaminergic...
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