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Dissecting the molecular mechanism of nuclear receptor action: transcription coactivators and corepressors

Lee JW, Cheong JH, Lee YC, Na SY, lee SK

  • KMID: 1109302
  • Exp Mol Med.
  • 2000 Jun;32(2):53-60.
No abstract available.
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Differential Expression of Stem Cell Markers and Vascular Endothelial Growth Factor in Human Retinoblastoma Tissue

Kim M, Kim JH, Kim JH, Kim DH, Yu YS

PURPOSE: To investigate the relationship between vascular endothelial growth factor (VEGF) and the cancer stem cell-vascular niche complex in human retinoblastoma tissue. METHODS: Six human retinoblastoma specimens primarily enucleated for...
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Composite Follicular Variant of Papillary Carcinoma and Mucoepidermoid Carcinoma of Thyroid Gland: A Case Report

Jung YH, Kang MS

A 50-yr-old male presented a thyroid mass with dysphasia and hoarseness. He underwent total thyroidectomy and neck node dissection. Pathologically, the tumor had two distinct tumor components with intermingled areas:...
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Mutation and expression of the p27KIP1 and p57KIP2 genes in human gastric cancer

Shin JY, Kim HS, Lee KS, Kim JB, Park JB, Won MH, Chae SW, Choi YH, Choi KC, Park YE, Lee JY

  • KMID: 1109306
  • Exp Mol Med.
  • 2000 Jun;32(2):79-83.
Cyclin-dependent kinase inhibitors (CDKI) are negative regulators of cell cycle progression by binding the cyclin-CDK complex and inhibiting the CDK activity. Genetic alteration in the CDKI genes has been implicated...
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Nucleolus contains signal molecules that constitute membrane-nucleolus linked pathway

Jeong JS, Kim IH, Lee HJ, Choi YC

  • KMID: 755010
  • Exp Mol Med.
  • 1998 Dec;30(4):205-213.
Since there have been very few studies on nucleolar signaling, an attempt was made to establish nucleolar signal pathways which link the cell membrane to the nucleolus for the transfer...
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The effects of transferring tumor suppressor gene p16INK4A to p16INK4A-deleted cancer cells

Lee KY, Yoo CG, Han SK, Shim YS, Kim YW

  • KMID: 759084
  • Korean J Intern Med.
  • 1999 Jan;14(1):53-58.
OBJECTIVES: p16 is known to be an important tumor suppressor gene and is also called MTS1 (multiple tumor suppressive gene 1). Especially in the case of non-small cell...
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Gastrointestinal Metastasis from a Primary Adenocarcinoma of the Lung Presenting with Acute Abdominal Pain

Hsing CT, Kim HY, Lee JH, Han JS, Lee JH, Chang JS, Choi SR, Jeong JS

Symptomatic gastro-intestinal metastasis in lung cancer is extremely rare and only a few case reports have been published. Here, we report a case with lung adenocarcinoma that presented with acute...
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Characterization of cis-acting elements in the rat ATP citrate-lyase gene promoter

Moon YA, Park SW, Kim KS

  • KMID: 1093599
  • Exp Mol Med.
  • 2002 Mar;34(1):60-68.
The cis-acting element in the promoter of the rat ATP-citrate lyase (ACL) and transcription factors which interact with these elements were determined. Six Sp1 binding sites and CAAT box exist...
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Influence of the sequence variations of the HLA-DR promoters derived from human melanoma cell lines on nuclear protein binding and promoter activity

Lee TJ, Kim SJ, Park JH

In previous studies we reported that the expression of HLA-DR on melanoma cell lines was differentially modulated by IFN- gamma and that the transcription rate was responsible for this differential...
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