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Genomic Profiling of Prostate Cancer: An Updated Review

Hatano K, Nonomura N

Understanding the genomic profiling of prostate cancer is crucial, owing to the emergence of precision medicine to guide therapeutic approaches. Over the last decade, integrative genomic profiling of prostate tumors...
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Role of Androgen Receptor in Prostate Cancer: A Review

Fujita K, Nonomura N

Androgen receptor (AR) is a steroid receptor transcriptional factor for testosterone and dihydrotestosterone consisting of four main domains, the N-terminal domain, DNA-binding domain, hinge region, and ligand-binding domain. AR plays...
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Erectile Dysfunction in Germ Cell Tumor Survivors

Okada K, Fujita K, Fukuhara S, Kiuchi H, Uemura M, Imamura R, Nonomura N

Purpose: Germ cell tumors (GCTs) are the most common malignant neoplasms in adolescents and young adults, and most patients with these tumors can be completely cured. Therefore, maintaining quality of...
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Reduction of Severity of Recurrent Psychotic Episode by Sustained Treatment with Aripiprazole in a Schizophrenic Patient with Dopamine Supersensitivity: A Case Report

Tadokoro S, Nonomura N, Kanahara N, Hashimoto , Iyo M

Dopamine supersensitivity psychosis (DSP) is a type of acute exacerbation of recurrent psychosis caused by long-term treatment with antipsychotics in schizophrenic patients. Although DSP is exceedingly troublesome for clinicians, effective...
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Quality of life in recipients after renal transplantation: a single-center experience

Tanaka R, Imamura R, Fukae S, Taniguchi A, Nakazawa S, Yamanaka K, Takahara S, Nonomura N

Background: It is well known that renal transplantation can restore renal function and reduce complications associated with re-nal failure in patients with end-stage renal failure. On the other hand, whether...
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Firmicutes in Gut Microbiota Correlate with Blood Testosterone Levels in Elderly Men

Matsushita M, Fujita K, Motooka D, Hatano K, Hata J, Nishimoto M, Banno E, Takezawa K, Fukuhara S, Kiuchi H, Pan Y, Takao T, Tsujimura A, Yachida S, Nakamura S, Obara W, Uemura H, Nonomura N

Purpose: In males, testosterone levels have been implicated in various diseases. Recently, the influence of gut microbialderived compounds on host metabolism has become evident, and it has been suggested that...
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