- Effects of Nocodazole on Protein Synthesis Appratus of Tumor Cells
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Kim SH, Kim JY, Sung EG, Lee YC
- KMID: 1529461
- Korean J Anat.
- 1997 Jun;30(3):243-258.
Nocodazole is an anticancer agent that acts on microtubules or filaments. HeLa, Hep G2, A549, L929 and NIH/3T3 cell lines were cultivated in alpha-MEM with 3micrometer or 30micrometer nocodazole. To... -
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- Effects of Nocodazole on Extracellular Matrix Proteins of Cancer Cell Lines
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Jung BW, Kim JY, Lee YC
- KMID: 2030730
- Korean J Anat.
- 1997 Oct;30(5):521-534.
Nocodazole is an anticancer agent, well-known for its antimetastatic activity that acts on microtubules, microfilaments and extracellular matrix proteins. Hela, Hep G2, A549, L929, and NIH/3T3 cell lines were cultivated... -
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- Effects of Nocodazole on Fine Structures in Co-cultured Vascular Endothelial Cells and Cancer Cell Lines
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Kim JY, Song IH, Lee JY, Sung EK, Lee Y
- KMID: 2040091
- Korean J Anat.
- 1999 Aug;32(4):459-474.
Endothelial cells were isolated from the aortic intima of Sprague-Dawley species, rat. These cells and each cancer cell line (HeLa, Hep G2, A549, L929 and NIH/3T3 cells) were co-cultivated in... -
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- Transcriptional Regulation of H2B Histone Gene Expression by Nocodazole in HL-60 Cells
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Lim K, Hong YG, Lee MS, Son MY, Yun KA, Park JI, Yoon WH, Park SK, Hwang BD
- KMID: 2175113
- J Korean Cancer Assoc.
- 2000 Apr;32(2):407-416.
PURPOSE: Nocodazole, a microtubule disrupting reagent, is known to arrest cells in the M phase, To gain insight on the regulatory mechanism of H2B histone gene expression by nocodazole in HL-60 cell,... -
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- RNA-sequencing Profiles of Cell Cycle–Related Genes Upregulated during the G2-Phase in Giardia lamblia
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Kim J, Shin MY, Park SJ
- KMID: 2448151
- Korean J Parasitol.
- 2019 Apr;57(2):185-189.
- doi: 10.3347/kjp.2019.57.2.185
To identify the component(s) involved in cell cycle control in the protozoan Giardia lamblia, cells arrested at the G1/S- or G2-phase by treatment with nocodazole and aphidicolin were prepared from... -
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- The Role of Microtubule in the Regulation of Endochondral Bone Formation in the Developing Mouse Cranial Base
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Kwon HJ, Lee JM, Cho KW, Shin JO, Cho SW, Lee MJ, Jung HS
- KMID: 1449629
- Korean J Phys Anthropol.
- 2011 Jun;24(2):105-112.
Endochondral bone formation of the developing cranial base is a complex process. This mechanism requires precise orchestration of many cellular events and cartilage matrix metabolism, such as proliferation, becoming round... -
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- Development of an Efficient Method for Obtaining Metaphase Chromosomes in Individual Blastomeres of Mouse and Human Preimplantaion Embryos: Effect of Microtubule Depolymerizing Agents
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Lim CK, Min DM, Lee HS, Kim JY, Koong MK, Kang IS, Jun JH
- KMID: 1979046
- Korean J Fertil Steril.
- 2003 Jun;30(2):111-118.
OBJECTIVES: The development of an useful method for obtaining metaphase chromosomes from a biopsied blastomere would allow differentiation between embryos with balanced and normal chromosome complements in the preimplantation genetic... -
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- Role of ATF on Transcriptional Regulation of DNA Topoisomerase II a Gene in HL - 60 Arrested to G2 / M and M Phase
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Lim K, Son MY, Choi BI, Yun KA, Zheng M, Kang TW, Lee YC, Park JI, Yoon WH, Hwang BD
- KMID: 2175140
- J Korean Cancer Assoc.
- 1999 Dec;31(6):1279-1287.
PURPOSE: To gain insight on transcriptional repression of Topo II a in HL-60 cells arrested to G2/M and M phase, the levels of Topo IIa mRNA and the binding activity... -
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- Sec13 induces genomic instability in U2OS cells
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Sihn CR, Suh EJ, Lee KH, Kim SH
- KMID: 1056239
- Exp Mol Med.
- 2005 Jun;37(3):255-260.
Sec13p has been known as an endoplasmic reticulum-Golgi transport protein. Recently, it has also been shown to be required for the formation of septation in the fission yeast Schizosaccharomyces pombe.... -
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- Disruption of Microtubules Sensitizes the DNA Damage-induced Apoptosis Through Inhibiting Nuclear Factor kappaB (NF-kappaB) DNA-binding Activity
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Lee H, Jeon J, Ryu YS, Jeong JE, Shin S, Zhang T, Kang SW, Hong JH, Hur GM
- KMID: 1779226
- J Korean Med Sci.
- 2010 Nov;25(11):1574-1581.
- doi: 10.3346/jkms.2010.25.11.1574
The massive reorganization of microtubule network involves in transcriptional regulation of several genes by controlling transcriptional factor, nuclear factor-kappa B (NF-kappaB) activity. The exact molecular mechanism by which microtubule rearrangement... -
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