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Alteration of nitrergic neuromuscular transmission as a result of acute experimental colitis in rat

Sung TS, La JH, Kim TW, Yang IS

Nitric oxide (NO) is a non-adrenergic, non-cholinergic neurotransmitter found in the enteric nervous system that plays a role in a variety of enteropathies, including inflammatory bowel disease. Alteration of nitrergic neurons has been reported...
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Gastrointestinal Motility Changes and Myenteric Plexus Alterations in Spontaneously Diabetic Biobreeding Rats

Demedts I, Masaoka T, Kindt S, De Hertogh G, Geboes K, Farre R, Vanden Berghe P, Tack J

  • KMID: 2325788
  • J Neurogastroenterol Motil.
  • 2013 Apr;19(2):161-170.
BACKGROUND/AIMS: Type 1 diabetes is often accompanied by gastrointestinal motility disturbances. Vagal neuropathy, hyperglycemia, and alterations in the myenteric plexus have been proposed as underlying mechanism. We therefore studied the...
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Relaxing Effect of Acetylcholine on Phenylephrine-Induced Contraction of Isolated Rabbit Prostate Strips Is Mediated by Neuronal Nitric Oxide Synthase

Nguyen HB, Lee SY, Park SH, Lee MY, Chang IH, Myung SC

PURPOSE: The location of acetylcholinesterase-containing nerve fibers suggests a role for acetylcholine in both contractility and secretion in the prostate gland. The colocalization of nitrergic nerves with cholinergic nerves, and...
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Comparison of Changes in the Interstitial Cells of Cajal and Neuronal Nitric Oxide Synthase-positive Neuronal Cells With Aging Between the Ascending and Descending Colon of F344 Rats

Lee SM, Kim N, Jo HJ, Park JH, Nam RH, Lee HS, Kim HJ, Lee MY, Kim YS, Lee DH

  • KMID: 2395429
  • J Neurogastroenterol Motil.
  • 2017 Oct;23(4):592-605.
  • doi: 10.5056/jnm17061
BACKGROUND/AIMS: Neuronal degeneration and changes in interstitial cells of Cajal (ICCs) are important mechanisms of age-related constipation. This study aims to compare the distribution of ICCs and neuronal nitric oxide...
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Alterations of Colonic Contractility in an Interleukin-10 Knockout Mouse Model of Inflammatory Bowel Disease

Park JH, Kwon JG, Kim SJ, Song DK, Lee SG, Kim ES, Cho KB, Jang BI, Kim DH, Sin JI, Kim TW, Song IH, Park KS

  • KMID: 2381231
  • J Neurogastroenterol Motil.
  • 2015 Jan;21(1):51-61.
  • doi: 10.5056/jnm14008
BACKGROUND/AIMS: Inflammatory bowel disease is commonly accompanied by colonic dysmotility and causes changes in intestinal smooth muscle contractility. In this study, colonic smooth muscle contractility in a chronic inflammatory condition...
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