- Lysophosphatidylglycerol inhibits formyl peptide receptor like-1-stimulated chemotactic migration and IL-1beta production from human phagocytes
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Shim JW, Jo SH, Kim SD, Lee HY, Yun J, Bae YS
- KMID: 1119324
- Exp Mol Med.
- 2009 Aug;41(8):584-591.
- doi: 10.3858/emm.2009.41.8.064
In this study, we observed that lysophosphatidylglycerol (LPG) completely inhibited a formyl peptide receptor like-1 (FPRL1) agonist (MMK-1)-stimulated chemotactic migration in human phagocytes, such as neutrophils and monocytes. LPG also... -
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- Enhanced neutrophil functions by recombinant human granulocyte colony-stimulating factor in diabetic patients with foot infections in vitro
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Peck KR, Son DW, Song JH, Kim S, Oh MD, Choe KW
- KMID: 1066492
- J Korean Med Sci.
- 2001 Feb;16(1):39-44.
- doi: 10.3346/jkms.2001.16.1.39
This study was performed to evaluate the effect of granulocyte-colony stimulating factor on neutrophil functions in diabetic patients with active foot infections in vitro. Twelve diabetic patients with foot infections... -
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- LL-37 inhibits serum amyloid A-induced IL-8 production in human neutrophils
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Lee HY, Kim SD, Shim JW, Lee SY, Yun J, Bae YS
- KMID: 1123806
- Exp Mol Med.
- 2009 May;41(5):325-333.
- doi: 10.3858/emm.2009.41.5.036
Serum amyloid A (SAA) has been regarded as an important mediator of inflammatory responses. The effect of several formyl peptide receptor-like 1 (FPRL1) ligands on the production of IL-8 by... -
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- Inhibition of Janus activated kinase-3 protects against myocardial ischemia and reperfusion injury in mice
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Oh YB, Ahn M, Lee SM, Koh HW, Lee SH, Kim SH, Park BH
- KMID: 2154242
- Exp Mol Med.
- 2013 May;45(5):e23.
Recent studies have documented that Janus-activated kinase (JAK)-signal transducer and activator of transcription (STAT) pathway can modulate the apoptotic program in a myocardial ischemia/reperfusion (I/R) model. To date, however, limited... -
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- Heparin attenuated neutrophil infiltration but did not affect renal injury induced by ischemia reperfusion
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Shin CS, Han JU, Kim JL, Schenarts , Traber LD, Hawkins H, Traber DL
- KMID: 699941
- Yonsei Med J.
- 1997 Jun;38(3):133-141.
- doi: 10.3349/ymj.1997.38.3.133
Although heparin is better known as an anticoagulant, it also has several anti-inflammatory effects. Heparin is known to inhibit neutrophil adhesion, chemotaxis and oxygen free radical production. In... -
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- Calyculin A modulates activation of the NADPH-oxidase in Me2SO-differentiated HL-60 cells
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Park JI, Uhlinger D, Chung BS, Kim IH, Kwak JY
- KMID: 755011
- Exp Mol Med.
- 1998 Dec;30(4):214-220.
Human promyelocytic leukemia cells (HL-60) have been used as a model system in which to study the effects of protein phosphatase inhibitors on NADPH-oxidase activation. Since O2- is generated by... -
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- Enhanced Serum Neutrophil Chemotactic Activity was Noted in Both Early and Late Asthmatic Responses During Lysine-Aspirin Bronchoprovocation Test in ASA-Sensitive Asthmatic Patients
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Kim SS, Park HS, Yoon HJ, Lee YM, Lee SK, Nahm DH
- KMID: 1099791
- J Korean Med Sci.
- 2003 Feb;18(1):42-47.
- doi: 10.3346/jkms.2003.18.1.42
To investigate the pathogenic mechanism of late asthmatic response in comparison to early asthmatic response, changes of serum neutrophil chemotactic activity (NCA) using the Boyden chamber method and histamine level... -
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