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MTT and Neutral red Biologic Assay for Human Bladder Cancer Cell Line(TCC-SuP) and Androgen Stimulated Cell Line of Mouse (SC-115): In Vitro Chemosensitivity Test

Kim BW, Kim DY, Chung SK, Chang SK

  • KMID: 2289661
  • Korean J Urol.
  • 1990 Oct;31(5):635-640.
To overcome the limitations of clonogenic assay (low plating efficiencies, clumping artifacts, long assay duration), we performed chemosensitivity test using MTT and neutral red biologic assay on SC-115 (androgen stimulated...
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Simultaneous Stain with Neutral Red and Tetrazolium Salt for Experimental Cerebral Infarction Morphometry

Seo JH, Park YK, Kim MH, Chong YG, Chung HS, Suh JK, Lee HK, Chu JW, Lee KC

  • KMID: 2187809
  • J Korean Neurosurg Soc.
  • 1992 Aug;21(8):990-998.
Serial changes in the size of infracted area induced by MCA occlusion(MCAO) were compared with Neutral Red(NR) and 2, 3, 5-Triphenyl tetrazolium chloride(TTC) stains. The differences in size of the...
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Application of Neutral Red Staining for the Evaluation ofthe Viability of Dermatophytes

Park JK, Lee WJ, Suhr KB, Lee JH

  • KMID: 2230718
  • Korean J Dermatol.
  • 1996 Feb;34(1):122-126.
BACKGROUND: Microsopic examination of potassium hydroxide(KOH) preparation and fungus culture is required for the diagnosis of fungal infection. Sometimes dermatophytes fail to grow on culture medium, although these are observed...
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The Effect of Halothane-induced Acidosis on Focal Cerebral Ischemia in Rat

Han KS, Lee KC, Chu JW, Lee HK

  • KMID: 1693608
  • J Korean Neurosurg Soc.
  • 1993 Aug;22(8):877-883.
The current study was performed to investigate the influence of acidosis on focal cerebral ischemia in view of morphometric assay and neuropathological examination. The acidosis was induced by increment of...
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A Study of a Selection of Antidotes for Paraquat induced Skin Damage

Kim BS, Eun HC, Lee HG, Chung JH

BACKGROUND: Paraquat is a widely used herbicide, known to cause lethal toxicity in humans. Most studies about paraquat have concentrated on systemic toxicity, however several cases of paraquat-induced dermatitis have...
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Growth inhibition and induction of apoptosis in cervical cancer cell lines by green tea polyphenols

Jin YM, Nam SL, Ahn WS

  • KMID: 2262704
  • Korean J Obstet Gynecol.
  • 2002 Apr;45(4):560-568.
OBJECTIVE: The purpose of this article is to estimate the anti-cancer effects of the major components of the green tea (polyphenols, catechin and EGCG) and the mechanism of EGCG on...
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Inhibitory Effect of Rotundarpene on Parkinsonian Neurotoxin 1-Methyl-4-Phenylpyridinium-Induced Apoptotic Cell Death

Han SW, Lee CS, Hwang IH, Han JH, Kim DE

BACKGROUND: The extract and hemiterpene glycosides of Ilex Rotunda Thunb exert antioxidant and anti-inflammatory effects. The effect of rotundarpene on apoptosis in neuronal cells caused by the 1-methyl-4-phenylpyridinium (MPP⁺) has...
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The Influence of Hyperglycemia on the Extent of Focal Cerebral Ischemia

Kwon TH, Park YK, Chong YK, Chung HS, Suh JK, Lee HK, Chu JW, Lee KC

  • KMID: 2019514
  • J Korean Neurosurg Soc.
  • 1992 Jan;21(1):81-89.
The present study was undertaken to investigate the influence of hyperglycemia on focal cerebral ischemia in view of morphometric assay and neuropathological examination. Forty Sprague-Dawley rats were divided into two...
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Autoproliferation of Fibroblast by Exposure to Crystalline Silica - Evaluation by H2O2 and PDGF-AA and TGF beta

Ahn BY, Kim KA, Mun JH, Jeong JS, Kim EK, Lim Y

  • KMID: 2028100
  • Korean J Occup Environ Med.
  • 2000 Jun;12(2):209-217.
OBJECTIVES: The aim of this study is to find out the activity of autoproliferation of ratfibroblast exposed to crystalline silica and the role of mediators secreted from rat fibroblast. METHODS: The...
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Antiplasmodial and Cytotoxic Activities of Toad Venoms from Southern Amazon, Brazil

Banfi FF, Guedes KD, Andrighetti CR, Aguiar AC, Debiasi BW, Noronha JD, Rodrigues , Júnior GM, Sanchez BA

The drug-resistance of malaria parasites is the main problem in the disease control. The huge Brazilian biodiversity promotes the search for new compounds, where the animal kingdom is proving to...
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Preventive Effect of Green Tea Extracts on the Inhibition of Connexin Expression Induced by Carcinogen H2O2

Choi SJ, Choung YH

  • KMID: 2276868
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Apr;51(4):355-362.
BACKGROUND AND OBJECTIVES: Carcinogens result in the impairment of intercellular communication as well as intracellular communication of normal cells. Connexin (Cx) is a main constituent protein of gap junctions that...
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Incidence of Vaculating Toxin Producing Helicobacter pylori from Patients with Gastric Diseases

Kim CK, Jeong SS, Lee GC, Suh DH, Song GY, Choi KH, Chang MW

  • KMID: 2251450
  • Korean J Med.
  • 1998 May;54(5):675-683.
OBJECTIVES: This study was carried out to survey the prevalence of Helicobacter pylori infection and the incidence of vacuolating toxin producing H. pylori. A further aim of this study was...
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Microencapsulated Bovine Adrenal Medullary Chromaffin Cells Transplanted into Rat Spinal Cord Alleviated Cold Allodynia

Baek WY, Kim HG, Kim YM, Lim JO, Jeon YH

BACKGROUND: The intrathecal grafting of adrenal chromaffin cells as a potential analgesic source, to delivery analgesic substances such as catecholamines and opioid peptides, is known to be effective at treating...
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The Study on cell death induced by tumor necrosis factor alpha

Won YH, Lim MH, Kim DY, Chun IK

  • KMID: 2275062
  • Chonnam Med J.
  • 1996 Dec;32(2):177-186.
BACKGROUND: Tumor necrosis factor alpha(TNF) is a pleiotropic cytokine mainly produced by activated macrophages. Besides its role in the inflammation and immune function, TNF is specifically cytotoxic for many types...
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Evaluation of Cutaneous Irritancy Using Human Skin Recombinants

Kim BS, Lee DY, Han JH, Lee JH, Cho KH

  • KMID: 2038682
  • Korean J Dermatol.
  • 2002 Dec;40(12):1505-1517.
BACKGROUND: There is an increasing need for the development of in vitro models capable of substituting for animals in cutaneous irritancy studies. Until now, various culture models have been developed,...
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Growth Inhibition of Cervical Cancer Cell by Lipofectin with Adeno Associated Viral Plasmid [pAAVCMVp53/lipofectin]

Seo SY, Lee JY, An WS, Jo GN, Han YJ, Lee JM, Namkoong S, Lee HY, Kim SJ, Kim SP, Kim DJ, Park YS, Kim JK, Yang JM, Park SH

  • KMID: 2269620
  • Korean J Obstet Gynecol.
  • 1999 May;42(5):1108-1116.
PURPOSE: Cervical cancer is strongly associated with human papilloma virus [HPV] and the transforming viral genes E6 and E7 are steadily expressed by the tumor cells. To evaluate the...
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Cell-Specific Growth Inhibition of Human Cervical Cancer Cell by Recombinant Adenovirus p53 in vitro and in vivo

Bae SM, Kim YW, Yoon JH, Yoo JY, Seo YS, Nam SL, Lee JM, Namkoong S, Kim CK, Kim YW, Ahn WS

  • KMID: 2166176
  • Cancer Res Treat.
  • 2003 Jun;35(3):181-190.
PURPOSE: Despite the significance of the p53 adenoviral vector in cancer gene therapy, an advanced strategy for the development of preferential tumor cell-specific delivery and the long-term persistent gene expression...
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