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Neural cell adhesion molecule (NCAM) promotes the differentiation of hippocampal precursor cells to a neuronal lineage, especially to a glutamatergic neural cell type

Shin MH, Lee EG, Lee SH, Lee YS, Son H

  • KMID: 1121093
  • Exp Mol Med.
  • 2002 Dec;34(6):401-410.
Rat hippocampal precursor cells isolated from hippocampi of embryonic day 16.5 (E16.5) rat embryos were found to proliferate in the presence of basic fibroblast growth factor. Addition of soluble...
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Toxic effects of methylmercury, arsanilic acid and danofloxacin on the differentiation of mouse embryonic stem cells into neural cells

Kang SJ, Jeong SH, Kim EJ, Park YI, Park SW, Shin HS, Son SW, Kang HG

This study was performed to assess the neurotoxic effects of methylmercury, arsanilic acid and danofloxacin by quantification of neural-specific proteins in vitro. Quantitation of the protein markers during 14 days...
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The biologic role of ganglioside in neuronal differentiation: effects of GM1 ganglioside on human neuroblastoma SH-SY5Y cells

Lee MC, Lee WS, Park CS, Juhng SW

Human neuroblastoma SH-SY5Y cell is a cloned cell line which has many attractive features for the study of neuronal proliferation and neurite outgrowth, because it has receptors for insulin, IGF-I...
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Neurotoxicity Screening in a Multipotent Neural Stem Cell Line Established from the Mouse Brain

Choi YS, Lee MC, Kim HS, Lee KH, Park YG, Kim HK, Jeong HS, Kim MK, Woo YJ, Kim SU, Ryu JK, Choi HB

Neural stem cells (NSCs) have mainly been applied to neurodegeneration in some medically intractable neurologic diseases. In this study, we established a novel NSC line and investigated the cytotoxic responses...
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Protective effects of fustin, a flavonoid from Rhus verniciflua tokes, on 6-hydroxydopamine-induced neuronal cell death

Park BC, Lee YS, Park HJ, Kwak MK, Yoo BK, Kim JY, Kim JA

  • KMID: 1047082
  • Exp Mol Med.
  • 2007 Jun;39(3):316-326.
6-Hydroxydopamine (6-OHDA) is a neurotoxin and is commonly used to generate experimental models of Parkinson's disease (PD). In this study, we investigated the signaling molecules involved in the 6-OHDA-induced cell...
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