- Transcriptional Mechanisms of Drug Addiction
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Nestler EJ
- KMID: 1432535
- Clin Psychopharmacol Neurosci.
- 2012 Dec;10(3):136-143.
- doi: 10.9758/cpn.2012.10.3.136
Regulation of gene expression is considered a plausible mechanism of drug addiction given the stability of behavioral abnormalities that define an addicted state. Numerous transcription factors, proteins that bind to... -
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- Human Transcriptome and Chromatin Modifications: An ENCODE Perspective
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Shen L, Choi I, Nestler EJ, Won KJ
- KMID: 1494258
- Genomics Inform.
- 2013 Jun;11(2):60-67.
- doi: 10.5808/GI.2013.11.2.60
A decade-long project, led by several international research groups, called the Encyclopedia of DNA Elements (ENCODE), recently released an unprecedented amount of data. The ambitious project covers transcriptome, cistrome, epigenome,... -
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