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Lessons learned from 12,000 robotic radical prostatectomies: Is the journey as important as the outcome?

Kang SG, Shim JS, Onol F, Bhat KR, Patel VR

Robotic radical prostatectomy (RARP) is a standardized treatment for localized prostate cancer, which provides better functional outcomes and similar oncological outcomes compared to open approaches. Here, we share our experience...
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A Rare Cause of Thoracic Spinal Cord Compression by Multiple Large Tarlov Cysts

Kleib AS, Salihy SM, Hamdi H, Carron R, Soumaré O

Spinal extradural arachnoid cyst (SEAC) is a rare cause of spinal cord compression. Bifocal location of thoracic and sacral SEACs is rarely reported in the literature. We report a case...
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Effects of Exercise on Neuropathy in Streptozotocin-Induced Diabetic Rats

Lee EC, Kim MO, Roh GH, Hong SE

OBJECTIVE: To evaluate the effects of early regular exercise and to assess the electrophysiological and histopathological findings of the rat tail nerve in relation to the timing of exercise training...
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Field Cancerization in Sporadic Colon Cancer

Park SK, Song CS, Yang HJ, Jung YS, Choi KY, Koo DH, Kim KE, Jeong KU, Kim HO, Kim H, Chun HK, Park DI

BACKGROUND/AIMS: Aberrant DNA methylation has a specific role in field cancerization. Certain molecular markers, including secreted frizzled-related protein 2 (SFRP2), tissue factor pathway inhibitor 2 (TFPI2), N-Myc downstream-regulated gene 4...
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Chitosan/Graphene and Poly(D, L-Lactic-co-Glycolic Acid)/Graphene Nano-Composites for Nerve Tissue Engineering

Soltani S, Ebrahimian-Hosseinabadi M, Kharazi AZ

This study aimed at examining and comparing the fabrication process, electrical conductivity, and biological properties of Chitosan/Graphene membranes and poly(D, L-lactic-co-glycolic acid) (PLGA)/Graphene membranes. Nano-composite membranes were made using chitosan...
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Optical Biopsy of Peripheral Nerve Using Confocal Laser Endomicroscopy: A New Tool for Nerve Surgeons?

Crowe CS, Liao JC, Curtin CM

Peripheral nerve injuries remain a challenge for reconstructive surgeons with many patients obtaining suboptimal results. Understanding the level of injury is imperative for successful repair. Current methods for distinguishing healthy...
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Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies

Ciechanover A, Kwon YT

Mammalian cells remove misfolded proteins using various proteolytic systems, including the ubiquitin (Ub)-proteasome system (UPS), chaperone mediated autophagy (CMA) and macroautophagy. The majority of misfolded proteins are degraded by the...
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Analysis of ultrastructural changes in the rat sciatic nerve after exposure to pulsed radiofrequency using small angle X-ray scattering (SAXS)

Lee TH, Lee S, Kim JH, Jung JY, Kim BI, Shin TJ

  • KMID: 1908530
  • Anesth Pain Med.
  • 2014 Jul;9(3):209-216.
BACKGROUND: Pulsed radiofrequency (PRF) may be used in the treatment of patients with some pain syndromes that cannot be controlled by alternative techniques. The objective of the present study is...
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Toxic effects of methylmercury, arsanilic acid and danofloxacin on the differentiation of mouse embryonic stem cells into neural cells

Kang SJ, Jeong SH, Kim EJ, Park YI, Park SW, Shin HS, Son SW, Kang HG

This study was performed to assess the neurotoxic effects of methylmercury, arsanilic acid and danofloxacin by quantification of neural-specific proteins in vitro. Quantitation of the protein markers during 14 days...
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In Vivo Effects of Adipose-Derived Stem Cells in Inducing Neuronal Regeneration in Sprague-Dawley Rats Undergoing Nerve Defect Bridged with Polycaprolactone Nanotubes

Kim DY, Choi YS, Kim SE, Lee JH, Kim SM, Kim YJ, Rhie JW, Jun YJ

There have been many attempts for regeneration of peripheral nerve injury. In this study, we examined the in vivo effects of non-differentiated and neuronal differentiated adipose-derived stem cells (ADSCs) in...
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Valproic Acid Increases Expression of Neuronal Stem/Progenitor Cell in Spinal Cord Injury

Bang WS, Kim KT, Cho DC, Kim HJ, Sung JK

OBJECTIVE: This study investigates the effect of valproic acid (VPA) on expression of neural stem/progenitor cells (NSPCs) in a rat spinal cord injury (SCI) model. METHODS: Adult male rats (n=24) were...
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Characterization of nestin expression in astrocytes in the rat hippocampal CA1 region following transient forebrain ischemia

Cho JM, Shin YJ, Park JM, Kim J, Lee MY

Recent studies have suggested that nestin facilitates cellular structural remodeling in vasculature-associated cells in response to ischemic injury. The current study was designed to investigate the potential role of post-ischemic...
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Expression Profiles of F4/80 and Nestin in Ocular Immune Cells Following Pharmaceutically Induced Retinal Degeneration in Adult Mice

Ahn SI, Ohn YH, Park TK

PURPOSE: To evaluate the expression patterns of F4/80 and nestin in the ciliary body and the optic nerve following N-methyl-N-nitrosourea (NMU)-induced retinal degeneration in adult mice. METHODS: After intraperitoneal injection of...
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Genome-Wide Association Study of Lung Cancer in Korean Non-Smoking Women

Kim JH, Park K, Yim SH, Choi JE, Sung JS, Park JY, Choi YY, Jeon HS, Park JY, Yoon HK, Kim YH, Yoo BS, Kim YT, Hu HJ, Chung YJ, Kim H, Sung SW, Hong YC

Lung cancer in never-smokers ranks as the seventh most common cause of cancer death worldwide, and the incidence of lung cancer in non-smoking Korean women appears to be steadily increasing....
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Distribution of Peripherin Immunoreactive Axons in Rat Molar Pulp

Kim TH, Bae YC, Yang ES

Dental pulp is innervated mostly by unmyelinated axons and small myelinated axons. These axons are implicated pain transmission and contain various neurotransmitters and receptors. However, little information, so far, is...
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Intrathecal Lamotrigine Attenuates Antinociceptive Morphine Tolerance and Suppresses Spinal Glial Cell Activation in Morphine-Tolerant Rats

Jun IG, Kim SH, Yoon YI, Park JY

Glial cells play a critical role in morphine tolerance, resulting from repeated administration of morphine. Both the development and the expression of tolerance are suppressed by the analgesic lamotrigine. This...
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Attenuation of Spinal Cord Injury-Induced Astroglial and Microglial Activation by Repetitive Transcranial Magnetic Stimulation in Rats

Kim JY, Choi GS, Cho YW, Cho H, Hwang SJ, Ahn SH

Spinal cord injury (SCI) causes not only loss of sensory and motor function below the level of injury but also chronic pain, which is difficult and challenging of the treatment....
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Treatment of Recurrent Neuroma after Forearm Amputation: End to End Neurorrhaphy

Roh YT, Kim HM, You SL, Kim CJ, Park IJ

  • KMID: 1908174
  • Arch Reconstr Microsurg.
  • 2013 Nov;22(2):86-89.
The neuroma is a tumor of nerve tissue that partially or completely severed through incomplete regeneration process. Neuromas that formed in the stump of a limb following amputation is a...
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A Case of Synchronous Occurrence of Gastric Schwannoma and Gastric Adenoma

Kim EO, Kim DH, Byeon JH, Yu YJ, Jung SH, Jeon EJ, Oh JH, Lee S

Gastric schwannomas are rare benign tumors among the mesenchymal tumor of the gastrointestinal tract, arising from the nerve tissue which has a schwann cell sheath. These neoplasms are grossly similar...
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Neurochemical Properties of Dental Primary Afferent Neurons

Vang H, Chung G, Kim HY, Park SB, Jung SJ, Kim JS, Oh SB

The long belief that dental primary afferent (DPA) neurons are entirely composed of nociceptive neurons has been challenged by several anatomical and functional investigations. In order to characterize non-nociceptivepopulation among...
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