- Alternative Methods for Testing Botulinum Toxin: Current Status and Future Perspectives
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Nepal MR, Jeong TC
- KMID: 2503469
- Biomol Ther.
- 2020 Jul;28(4):302-310.
- doi: 10.4062/biomolther.2019.200
Botulinum toxins are neurotoxic modular proteins composed of a heavy chain and a light chain connected by a disulfide bond and are produced by Clostridium botulinum. Although lethally toxic, botulinum... -
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- Role of Intestinal Microbiota in Metabolism of Voglibose In Vitro and In Vivo
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Nepal MR, Kang MJ, Kim GH, Cha DH, Kim JH, Jeong TC
- KMID: 2513054
- Diabetes Metab J.
- 2020 Dec;44(6):908-918.
- doi: 10.4093/dmj.2019.0147
Background Voglibose, an α-glucosidase inhibitor, inhibits breakdown of complex carbohydrates into simple sugar units in intestine. Studies showed that voglibose metabolism in the liver might be negligible due to its poor... -
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- Pharmacokinetic Interaction of Chrysin with Caffeine in Rats
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Noh K, Oh DG, Nepal MR, Jeong KS, Choi Y, Kang MJ, Kang W, Jeong HG, Jeong TC
- KMID: 2351695
- Biomol Ther.
- 2016 Jul;24(4):446-452.
- doi: 10.4062/biomolther.2015.197
Pharmacokinetic interaction of chrysin, a flavone present in honey, propolis and herbs, with caffeine was investigated in male Sprague-Dawley rats. Because chrysin inhibited CYP1A-selective ethoxyresorufin O-deethylase and methoxyresorufin O-demethylase activities... -
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- Effects of Baicalin on Oral Pharmacokinetics of Caffeine in Rats
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Noh K, Nepal MR, Jeong KS, Kim SA, Um YJ, Seo CS, Kang MJ, Park PH, Kang W, Jeong HG, Jeong TC
- KMID: 2380355
- Biomol Ther.
- 2015 Mar;23(2):201-206.
- doi: 10.4062/biomolther.2014.134
Scutellaria baicalensis is one of the most widely used herbal medicines in East Asia. Because baicalein and baicalin are major components of this herb, it is important to understand the... -
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