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Effects of TNF-alpha on Angiogenesis in CT-26 Mouse Colon Carcinoma Homograft Model

Chun JW, Jung JT, Oh HK, Bae JY, Shin IH, Cho CH

  • KMID: 935194
  • Korean J Gastroenterol.
  • 2005 Dec;46(6):440-446.
BACKGROUND/AIMS: Tumor necrosis factor-alpha (TNF-alpha) exerts its anti-tumor effect through direct cytotoxicity on tumor cells and damage to the tumor vasculature. However, its role in tumor angiogenesis is controversial. We...
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Computational Analysis of Tumor Angiogenesis Patterns Using a Two-dimensional Model

Shim EB, Kwon YG, Ko HJ

Tumor angiogenesis was simulated using a two-dimensional computational model. The equation that governed angiogenesis comprised a tumor angiogenesis factor (TAF) conservation equation in time and space, which was solved numerically...
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