- Serum Neopterin Concentration in Children with Graves' Disease
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Jung SH, Song MY, Shu BK, Lee BC
- KMID: 2193916
- J Korean Soc Pediatr Endocrinol.
- 1998 May;3(1):68-72.
PURPOSE:Neopterin is a marker of activation of the T-lymphocyte/monocyte axis. We measured serum neopterin concentration to investigate whether serum neopterin levels are increased in children with Graves' disease and whether... -
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- Clinical significance of urinary neopterin excretion in patients with various digestive cancers
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Kim GJ, Kim HB, Lee SS, Lee MH, Lee SJ
- KMID: 1697991
- Korean J Intern Med.
- 1991 Oct;41(4):551-557.
No abstract available. -
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- Elevated Serum Levels of Neopterin in Patients with Behçet's Disease
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Yoon J, Lee SH, Bang D, Lee S, Kim JC, Chung TH
- KMID: 2361696
- Ann Dermatol.
- 1993 Jul;5(2):74-78.
- doi: 10.5021/ad.1993.5.2.74
BACKGROUND: Neopterin is released from monocytes/macrophages specifically by stimulation with interferon-γ. Therefore the increase refers to the activation of T lymphocytes. OBJECTIVE: Our objective was to examine the potential role of... -
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- Serum leceles of soluble interleukin-2 receptor and neopterin in patients with autoimmune thyroid disease
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Lee IK, Kim JC, Lee SK, Lee JT, Lee KB
- KMID: 1698096
- Korean J Intern Med.
- 1992 Mar;42(3):330-336.
No abstract available. -
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- Levels of Urinary Neopterin in Patients with Lepromatous Leprosy and Patients with Erythema Nodosum Leprosum
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Kim BC, Lee KS, Song JY, Kwak CS
- KMID: 2231319
- Korean J Dermatol.
- 1988 Jun;26(3):306-313.
In lepromatous leprosy, it is generally believed that there is not only defective CMl specific for M. leprae, but also generalized impairment of CMI and in erythema nodosum leprosum, an... -
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- Serum Neopterin in Head Injury
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Kang BJ, Kim DH, Hwang SK, Hamm IS, Park YM, Kim SL
- KMID: 1904185
- J Korean Neurosurg Soc.
- 1992 Jun;21(6):665-670.
Cell-mediated immunity frequently becomes impaired after major trauma. To investigate the immune response of the head injury, the authors measured the level of the serum neopterin, which represents the index... -
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- Neopterin as a Marker of Disease Activity in Childhood Acute Lymphocytic Leukemia
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Yoo BW, Song TW, Yoo CJ, Yang CH
- KMID: 2278267
- Korean J Pediatr Hematol Oncol.
- 2003 Apr;10(1):58-63.
PURPOSE: Neopterin is a degradation product derived from guanosin triphosphate (GTP) during biosynthesis of tetrahydrobiopterin. It is produced by human monocytes/macrophages upon stimulation with interferon-gamma from activated T lymphocytes. Therefore,... -
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- Changes of Serum Neopterin and Elastase - alpha1 - Antitrypsin
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Kim HJ, Chung SL, Kim JC, Kim MK
- KMID: 2085728
- Korean J Dermatol.
- 1994 Aug;32(4):547-553.
BACKGROUND: Generalized immune aetivation occurs early in the course of many infectious diseases. Clinical investigations have known that immune activation can be qiantified by the measurement of soluble immune activation... -
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- The Clinical Significance of Serum and Urinary Neopterin Levels in Several Renal Diseases
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Lhee HY, Kim H, Joo KJ, Jung SS, Lee KB
- KMID: 2157820
- J Korean Med Sci.
- 2006 Aug;21(4):678-682.
- doi: 10.3346/jkms.2006.21.4.678
Neopterin is a pyrazino-pyrimidine compound, and is known to be a marker associated with cell-mediated immunity in various diseases. We hypothesized that the levels of serum and urine neopterin would... -
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- Clinical Significance of Serum and Urinary Neopterin Levels in Some Renal Diseases
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Jung SS, Kim H, Yun JW, Suh JY, Jung CH, Lee KB
- KMID: 2254359
- Korean J Nephrol.
- 2004 Mar;23(2):241-247.
BACKGROUND: Neopterin is a pyrazino-pyrimidine compound, produced by human monocytes or macrophages primarily upon stimulation with gamma interferon. Neopterin is a marker associated with cell- mediated immunity. The levels of... -
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- Biochemical Analysis of Three Biological Fluids and its Response to Non-Surgical Periodontal Therapy in Pre and Postmenopausal Women with Periodontitis
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Prasanna J, Sumadhura
- KMID: 2466830
- J Menopausal Med.
- 2019 Dec;25(3):149-157.
- doi: 10.6118/jmm.18179
OBJECTIVES: Periodontitis is a common chronic inflammatory disease characterized by the destruction of the supporting structures of the teeth. The stages of menopause also worsen inflammatory condition. Biomarkers from biological... -
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- Cellular Immune Respones in Myasthenia Gravis
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Park SP, Park YC
- KMID: 1661087
- J Korean Neurol Assoc.
- 1994 Mar;12(1):41-50.
To investigate the cellular immune response in myasthenia gravis (MG), serum levels of interleukin-2(IL-2), soluble IL-2 receptor(sIL-2R) and neopterin were measured in 48 patients with MG, and these levels were... -
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- Serum Interleukin-2, Soluble Interleukin-2 Receptors and Neopterin Concentrations in Guillain-Barre Syndrome
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Lim JG, Park YC, Kim JC
- KMID: 2342403
- J Korean Neurol Assoc.
- 1994 Jun;12(2):279-288.
Guillain-Barre syndrome (GBS) is an autoimmune disease with an acute evolution of inflammatory demyelinating polyradiculoneuropathy. Although the precise immune mechanisms and involved antigens are uncertain, both humoral and cellular immune... -
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- Comparative Evaluation of Salivary Neopterin Levels and Its Effects to Periodontal Therapy in Pre- and Post-Menopausal Women
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Prasanna J, Sumadhura , Karunakar , Rohini N
- KMID: 2378222
- J Menopausal Med.
- 2017 Apr;23(1):32-41.
- doi: 10.6118/jmm.2017.23.1.32
OBJECTIVES: Neopterin is a valuable diagnostic biomarker, which is elevated in inflammatory conditions like periodontitis, that is characterized by destruction of the supporting structures of the teeth. Among the biomarkers,... -
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- A Case of Dopa-Responsive Dystonia, Segawa Disease
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Kang HC, Lee HS, Kim HD
- KMID: 1582228
- J Korean Child Neurol Soc.
- 2004 May;12(1):99-104.
Segawa disease, hereditary progressive dystonia with marked diurnal fluctuations or defined dopa-responsive dystonia has age-dependent clinical courses, which are characterized with marked progression in the first one and half... -
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- Effects of general and spinal anesthetic techniques on endothelial adhesion molecules in cesarean section
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Honca M, Purtuloglu T, Akgul EO, Oztosun M, Honca T, Sizlan A, Agilli M, Aydin I, Yetim M, Aydin FN, Yaman H
- KMID: 1937755
- Korean J Anesthesiol.
- 2014 May;66(5):364-370.
- doi: 10.4097/kjae.2014.66.5.364
BACKGROUND: The aim of this study was to investigate the effects of anesthetic techniques used during general anesthesia (GA) and spinal anesthesia (SA) on endothelial adhesion molecules in the fetal... -
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- Two Cases of Tetrahydrobiopterin Deficiency
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Choi JW, Yang SW, Moon HR, Cho SC
- KMID: 2335149
- J Korean Pediatr Soc.
- 1995 Mar;38(3):397-403.
Tetrahydrobiopterin(BH4) deficiency is a rare type of hyperphenylalaninemia and usually leads to a progressive neurologic deterioration despite early dietary control of blood phenylalanine concentration. We experienced two cases of BH4... -
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- A study on the T lymphocyte subsets, plasma neopterin and serum lgE in patients with atopic dermatitis
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Suh SK, Kim MK, Kim SW, Jun JB, Chung SL
- KMID: 2230871
- Korean J Dermatol.
- 1993 Dec;31(6):877-883.
BACKGROUND: Many physiologic, pharmacologic and immunologic abnormalities were reported in atopic dermatitis but the cause and pathogenesis of the disease remain obscure. OBJECTIVE: This study was done to investigate the systemic... -
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- Neopterin Levels and Indoleamine 2,3-Dioxygenase Activity as Biomarkers of Immune System Activation and Childhood Allergic Diseases
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Ünüvar S, Erge D, Kılıçarslan B, Gözükara Bağ HG, Çatal F, Girgin G, Baydar T
- KMID: 2431606
- Ann Lab Med.
- 2019 May;39(3):284-290.
- doi: 10.3343/alm.2019.39.3.284
BACKGROUND: Although Th2 immune activation is predominant in allergic diseases, neopterinlevels and indoleamine 2,3-dioxygenase (IDO)-1 activity (kynurenine:tryptophan ratio), which reflect Th1 immune activity, increase with interferon-gamma (IFN-γ) stimulation. We investigated... -
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- Correlations between Coronary Plaque Tissue Composition Assessed by Virtual Histology and Blood Levels of Biomarkers for Coronary Artery Disease
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Ko YG, Le VC, Kim BH, Shin DH, Kim JS, Kim BK, Choi D, Jang Y, Hong MK
- KMID: 1776984
- Yonsei Med J.
- 2012 May;53(3):508-516.
- doi: 10.3349/ymj.2012.53.3.508
PURPOSE: We investigated correlations of coronary plaque composition determined by virtual histology (VH) intravascular ultrasound (IVUS) and blood levels of biomarkers that represent the vulnerability of coronary plaques. MATERIALS AND METHODS:... -
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