- Role of Long Non-coding Ribonucleic Acid in Gastrointestinal Cancer
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Park CH, Lee SK
- KMID: 1711287
- Korean J Gastroenterol.
- 2013 Dec;62(6):317-326.
- doi: 10.4166/kjg.2013.62.6.317
With the improvement of high-throughput genomic technology such as microarray and next-generation sequencing over the last ten to twenty year, we have come to know that the portion of the... -
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- Growth and Invasion of Sporadic Colorectal Adenocarcinomas in Terms of Genetic Change
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Roh SA, Choi EY, Cho DH, Jang SJ, Kim SY, Kim YS, Kim JC
- KMID: 1778028
- J Korean Med Sci.
- 2010 Mar;25(3):353-360.
- doi: 10.3346/jkms.2010.25.3.353
Integrative genetic changes were examined in relation to tumor growth and progression of sporadic colorectal cancers. Ninety-two sporadic colorectal cancer patients and 12 human colorectal cancer cell lines were evaluated.... -
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- Preclinical studies for pharmacokinetics and biodistribution of Ad-stTRAIL, an adenovirus delivering secretable trimeric TRAIL for gene therapy
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Kim CY, Park SH, Jeong M, Kwon OS, Doh H, Kang SH, Robbins PD, Kim BM, Seol DW, Kim BG
- KMID: 1123370
- Exp Mol Med.
- 2011 Oct;43(10):580-586.
- doi: 10.3858/emm.2011.43.10.065
Malignant glioma is the most frequent type in brain tumors. The prognosis of this tumor has not been significantly improved for the past decades and the average survival of patients... -
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- The Combination of TRAIL Treatment and Cancer Cell Selective Expression of TRAIL-Death Receptor DR4 Induces Cell Death in TRAIL-Resistant Cancer Cells
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Choi E, Kim Y, Kim K
- KMID: 1715873
- Yonsei Med J.
- 2006 Feb;47(1):55-62.
- doi: 10.3349/ymj.2006.47.1.55
The human telomerase reverse transcriptase (hTERT) promoter can be used for the tumor-specific expression of transgenes in order to induce selective cancer cell death. The hTERT core promoter is active... -
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- The pleckstrin homology domain of phospholipase D1 accelerates EGFR endocytosis by increasing the expression of the Rab5 effector, rabaptin-5
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Park MH, Choi KY, Min DS
- KMID: 2359887
- Exp Mol Med.
- 2015 Dec;47(12):e200.
- doi: 10.1038/emm.2015.101
Endocytosis is differentially regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) and phospholipase D (PLD). However, the relationship between HIF-1alpha and PLD in endocytosis is unknown. HIF-1alpha is degraded through the prolyl hydroxylase... -
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- LYR71, a derivative of trimeric resveratrol, inhibits tumorigenesis by blocking STAT3-mediated matrix metalloproteinase 9 expression
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Kim JE, Kim HS, Shin YJ, Lee CS, Won C, Lee SA, Lee JW, Kim Y, Kang JS, Ye SK, Chung MH
- KMID: 1104805
- Exp Mol Med.
- 2008 Oct;40(5):514-522.
- doi: 10.3858/emm.2008.40.5.514
Tumor migration/invasion is the main cause of tumor progression and STAT3 is needed to enhance tumor migration/invasion by up-regulating MMP-9. Thus, agents that inhibit STAT3 activation may be used as... -
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- Role of p21CIP1 as a determinant of SC-560 response in human HCT116 colon carcinoma cells
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Lee E, Choi MK, Han IO, Lim SJ
- KMID: 1094159
- Exp Mol Med.
- 2006 Jun;38(3):325-331.
SC-560, a strucutral analogue of celecoxib, induces growth inhibition in a wide range of human cancer cells in a cyclooxygenase (COX)-independent manner. Since SC-560 suppresses the growth of cancer cells... -
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- Secretion of Biologically Active Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor by Transduced Gastric Cancer Cells
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Kim HY, Park GS, Shin HJ, Park S, Kim K, Kim HI
- KMID: 1084502
- Yonsei Med J.
- 2008 Apr;49(2):279-287.
- doi: 10.3349/ymj.2008.49.2.279
PURPOSE: Gastric cancer has the highest incidence rate among cancers in Asia. The advanced type of signet ring cell carcinoma has poor prognosis compared to other types of gastric cancer.... -
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