- Characterization of the Indirubin Derivative LDD970 as a Small Molecule Aurora Kinase A Inhibitor in Human Colorectal Cancer Cells
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Ndolo KM, Park KR, Lee HJ, Yoon KB, Kim YC, Han SY
- KMID: 2376868
- Immune Netw.
- 2017 Apr;17(2):110-115.
- doi: 10.4110/in.2017.17.2.110
Aurora kinase A plays an essential role in mitosis including chromosome separation and cytokinesis. Aberrant expression and activity of Aurora kinase A is associated with numerous malignancies including colorectal cancer... -
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- Discovery of an Indirubin Derivative as a Novel c-Met Kinase Inhibitor with In Vitro Anti-Tumor Effects
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Ndolo KM, An SJ, Park KR, Lee HJ, Yoon KB, Kim YC, Han SY
- KMID: 2442014
- Biomol Ther.
- 2019 Feb;27(2):216-221.
- doi: 10.4062/biomolther.2018.091
The c-Met protein is a receptor tyrosine kinase involved in cell growth, proliferation, survival, and angiogenesis of several human tumors. Overexpression of c-Met has been found in gastric cancers and... -
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