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Intracellular Bacterial Infection and Invariant NKT Cells

Emoto M, Emoto Y

The invariant (i) natural killer (NK)T cells represent a unique subset of T lymphocytes which express the V alpha14 chain of the T cell receptor (TCR), that recognizes glycolipid antigens...
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The requirement of natural killer T-cells in tolerogenic APCs-mediated suppression of collagen-induced arthritis

Jung S, Park YK, Shin JH, Lee H, Kim SY, Lee GR, Park SH

TGF-beta-induced tolerogenic-antigen presenting cells (Tol-APCs) could induce suppression of autoimmune diseases such as collagen-induced arthritis (CIA) and allergic asthma. In contrast, many studies have shown that NKT cells are involved...
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The presence of CD8+ invariant NKT cells in mice

Lee H, Hong C, Shin J, Oh S, Jung S, Park YK, Hong S, Lee GR, Park SH

Invariant natural killer T (iNKT) cells develop in the thymus upon recognition of CD1d expressed on developing thymocytes. Although CD4 and CD8 coreceptors are not directly involved in the interaction...
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