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High Seroprevalence and Index of Anti-John-Cunningham Virus Antibodies in Korean Patients with Multiple Sclerosis

Kim SH, Kim Y, Jung JY, Park NY, Jang H, Hyun JW, Kim HJ

BACKGROUND AND PURPOSE: The anti-John-Cunningham virus (JCV)-antibody serostatus and index are used in the risk stratification of progressive multifocal leukoencephalopathy (PML) in multiple sclerosis (MS) patients treated with natalizumab. However,...
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Systematic review of the published data on the worldwide prevalence of John Cunningham virus in patients with multiple sclerosis and neuromyelitis optica

Paz SP, Branco L, Pereira MA, Spessotto , Fragoso YD

OBJECTIVES: John Cunningham virus (JCV) is a polyoma virus that infects humans, mainly in childhood or adolescence, and presents no symptomatic manifestations. JCV can cause progressive multifocal leukoencephalopathy (PML) in...
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Interferon beta-1b Treatment in a Korean Girl with Multiple Sclerosis

Kim HJ, Kim HD, Lee JS, Kang HC

  • KMID: 2329623
  • J Korean Child Neurol Soc.
  • 2013 Mar;21(1):28-32.
Here we report a case of pediatric multiple sclerosis treated with interferon beta-1b. Interferon beta is widely used in adult patients with multiple sclerosis (MS). However, its effects and safety...
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Targeted Therapy in Inflammatory Bowel Disease; Current Status and Future Perspectives

Jang BI

Novel biologic agents that selectively target specific molecules and pathways have been developed recently for the management of inflammatory bowel disease (IBD). Anti-TNF-alpha, an antibody to TNF-alpha is one of...
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Multiple Sclerosis

Kim W, Kim HJ

Multiple sclerosis (MS) is an inflammatory autoimmune disorder of the central nervous system (CNS) and one of the most common disabling neurological diseases of young adults. Although the exact mechanisms...
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