- Applications of kidney organoids derived from human pluripotent stem cells
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Kim YK, Nam SA, Yang CW
- KMID: 2415990
- Korean J Intern Med.
- 2018 Jul;33(4):649-659.
- doi: 10.3904/kjim.2018.198
The establishment of protocols to differentiate kidney organoids from human pluripotent stem cells provides potential applications of kidney organoids in regenerative medicine. Modeling of renal diseases, drug screening, nephrotoxicity testing... -
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- Effects of Dehydration on Vasopressin and Oxytocin Immunoreactive Neurons of the Hypothalamus in the Mongolian Gerbil
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Yoo GC, Yoon SS, Nam SA, Jo SM, Choi CD, Choi WB
- KMID: 2224613
- Korean J Anat.
- 1997 Dec;30(6):741-751.
The effects of dehydration on vasopressin and oxytocin immunoreactive neurons in the hypothalamus was investigated by using a immunohistochemistry. Adult Mongolian gerbil[Meriones unguiculates] were deprived of drinking water. Dehydrated animals... -
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- Indoleamine-accumulating cell death and endogenous glial cell reaction induced by 5,7-dihydroxytryptamine in the cat retina
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Jo SM, Nam SA, Yoon SS, Ko BM, Choi CD, Choi WB, Chun MH
- KMID: 1038170
- J Korean Med Sci.
- 1998 Aug;13(4):414-422.
- doi: 10.3346/jkms.1998.13.4.414
We investigated the patterns of degenerative changes of indoleamine-accumulating cells (IACs) induced by 5,7-dihydroxytryptamine (5,7-DHT, 100 microg), and the glial reaction to the neurodegenerative changes of IACs in the... -
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- Cytotoxic Effect of 5, 7-DHT on the Endogenous Glial Cells in the Dorsal Raphe Nucleus of the Rat
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Chae JM, Jo SM, Nam SA, Yoon SS, Ko BM, Choi CD, Choi WB
- KMID: 2092650
- Korean J Anat.
- 1998 Feb;31(1):167-179.
This study was designed to clarify the cytotoxic effects of 5, 7-dihydroxytryptamine (5, 7-DHT) on the serotonergic neurons in the dorsal raphe nucleus, and to investigate the glial reaction during... -
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- Cytotoxic Effect of 5, 7-DHT on the Serotonergic Neurons in the Dorsal Raphe Nucleus of the Rat
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Chae JM, Jo SM, Nam SA, Yoon SS, Ko BM, Choi CD, Choi WB
- KMID: 2092649
- Korean J Anat.
- 1998 Feb;31(1):151-166.
This study was designed to clarify the cytotoxic effects of 5, 7-dihydroxytryptamine (5, 7-DHT) on the serotonergic neurons in the dorsal raphe nucleus, and to investigate the glial reaction during... -
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- Cytotoxic Effect of 6-OHDA on the Dopaminergic Neurons and Astrocytes in the Dorsal Raphe Nucleus of the Rat
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Hong ES, Nam SA, Jo SM, Kang TC, Won MH, Choi CD
- KMID: 2040100
- Korean J Anat.
- 1999 Aug;32(4):553-561.
This study was designed to clarify the cytotoxic effects of 6-hydroxydopamine (6-OHDA) on the dopaminergic neurons and astrocytes in the dorsal raphe nucleus (DRN), and to investigate neurodegenerative changes by... -
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- Molecular Analysis of the Y Chromosome in a 46,XY Female Phenotype
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Kim JW, Kim TJ, Park SY, Nam SA, Jun JY
- KMID: 1536936
- J Genet Med.
- 1999 Dec;3(1):5-10.
This is a case report of 46,XY female phenotype (46,XY karyotype, no pubic hair, blind vagina and absence of uterus)in an 18-year-old patient. To confirm whether a Y chromosome has... -
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- Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy
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Kim JW, Nam SA, Seo E, Lee JY, Kim D, Ju JH, Lim SW, Kim HL, Kim HW, Yang CW, Kim J, Kim DS, kim YK
- KMID: 2521738
- Korean J Intern Med.
- 2021 Nov;36(6):1420-1436.
- doi: 10.3904/kjim.2020.323
Background/Aims: Tacrolimus has been used as an immunosuppressive agent in organ transplantation. Despite the therapeutic benefits, tacrolimus’s use is limited due to its nephrotoxicity. To reduce tacrolimus nephrotoxicity, effective humanized... -
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- Notch signaling in the collecting duct regulates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in mice
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Choi A, Nam SA, Kim WY, Park SH, Kim H, Yang CW, Kim J, Kim YK
- KMID: 2416004
- Korean J Intern Med.
- 2018 Jul;33(4):774-782.
- doi: 10.3904/kjim.2016.230
BACKGROUND/AIMS: Mind bomb-1 (Mib1) encodes an E3 ubiquitin ligase, which is required for the initiation of Notch signaling. Recently, it was demonstrated that the renal collecting duct plays an important... -
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- Deep learning predicts the differentiation of kidney organoids derived from human induced pluripotent stem cells
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Park K, Lee JY, Lee SY, Jeong I, Park SY, Kim JW, Nam SA, Kim HW, Kim YK, Lee S
- KMID: 2540184
- Kidney Res Clin Pract.
- 2023 Jan;42(1):75-85.
- doi: 10.23876/j.krcp.22.017
Background: Kidney organoids derived from human pluripotent stem cells (hPSCs) contain multilineage nephrogenic progenitor cells and can recapitulate the development of the kidney. Kidney organoids derived from hPSCs have the... -
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- Analysis of Clinical Characteristics and Risk Factors to Neurosurgical Patients with Clostridium Difficile-Associated Diarrhea
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Kim YS, Jeon HJ, Nam SA, Cho BM, Park SH, Oh SM
- KMID: 2019921
- J Korean Neurotraumatol Soc.
- 2011 Oct;7(2):92-98.
- doi: 10.13004/jknts.2011.7.2.92
OBJECTIVE: The risk factors of Clostridium difficile-associated diarrhea (CDAD) are well known in medical part. However, there have been a few studies of CDAD about neurosurgical patients. The aim of... -
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