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Ethyl Acetate Fraction from Cudrania Tricuspidata Inhibits IL-1beta-Stimulated Osteoclast Differentiation through Downregulation of MAPKs, c-Fos and NFATc1

Lee EG, Yun HJ, Lee SI, Yoo WH

BACKGROUND/AIMS: The present study was performed to determine the effects of the ethyl acetate extract of Cudrania tricuspidata (EACT) on interleukin (IL)-1beta-stimulated receptor activator of NF-kappaB ligand (RANKL)-mediated osteoclast differentiation....
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Platinum nanoparticles reduce ovariectomy-induced bone loss by decreasing osteoclastogenesis

Kim WK, Kim JC, Park HJ, Sul OJ, Lee MH, Kim JS, Choi HS

  • KMID: 1397447
  • Exp Mol Med.
  • 2012 Jul;44(7):432-439.
Platinum nanoparticles (PtNP) exhibit remarkable antioxidant activity. There is growing evidence concerning a positive relationship between oxidative stress and bone loss, suggesting that PtNP could protect against bone loss by...
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Protein kinase C micron plays an essential role in hypertonicity-induced heat shock protein 70 expression

Lim YS, Lee JS, Huang TQ, Seo JS

Heat shock protein 70 (HSP70), which evidences important functions as a molecular chaperone and anti-apoptotic molecule, is substantially induced in cells exposed to a variety of stresses, including hypertonic stress,...
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