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NADPH Dehydrogenase Staining as a Promising Diagnostic Test for Neurogenic Impotence

Moon KH, Kim JW, Jung HC, Park TC, Kim JS, Suh JK

  • KMID: 1960296
  • J Korean Androl Soc.
  • 1997 Dec;15(2):103-109.
PURPOSE: To elucidate whether cavernous nitric oxide synthase reflects the status of the cavernous nerve in patients with erectile impotence. PATIENTS AND METHODS: Fifty-one impotent patients aged 32 to 62 (mean...
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NADPH Diaphorase Staining Retinal Cells in Streptozotocin-induced Diabetic Rat Retina

Lee SJ, Huh K

  • KMID: 2205362
  • J Korean Ophthalmol Soc.
  • 1998 Oct;39(10):2377-2384.
Nitric oxide(NO) is a free radical which serves a wide variety of functions on vascular tone, neurotransmission, immune cytotoxicity, and many others. Nitric oxide synthase(NOS) is the biosynthetic enzyme of...
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The Effect of Expressions of Vasoactive Intestinal Polypeptide and Nicotinamide Adenine Dinucleotide Phosphate Diaphorase in the Anterior Vaginal Wall on Female Urinary Incontinence and Sexual Function

Bang SI, Kim TN, Lee HJ, Lee JZ

  • KMID: 2293232
  • Korean J Urol.
  • 2004 Dec;45(12):1235-1240.
PURPOSE: We performed immunohistochemical analysis of vasoactive intestinal polypeptide (VIP) and nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase in the anterior vaginal wall, and we investigated their relations to the females...
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Role of Nitric Oxide in Proximal Urethral Relaxation of the Rat

Jung HC, Kim U, Park TC

  • KMID: 2290100
  • Korean J Urol.
  • 1997 Sep;38(9):921-930.
Recently, it is well established that nitric oxide synthase (NOS) produces nitric oxide (NO), which is known to act as an important neural mediator of smooth muscle relaxation in various...
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Effect of Aging on Androgen, Penile Structure and Nitric-oxide Synthase in Rat

Yim SH, Kim SW, Kang SH

  • KMID: 2293833
  • Korean J Urol.
  • 2005 Nov;46(11):1199-1204.
PURPOSE: The purpose of this study was to investigate the changes of serum testosterone, intracavernous pressure, expression of nitric-oxide synthase (NOS) and content of penile smooth muscle in aged rat. MATERIALS...
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Fasting-induced Down-regulation of NADPH-diaphorase in the Magnocellular PVN of Rats

Lee JY, Kang DW, Kim DG, Jahng JW

In this study, we examined if glucocorticoids are required for the fasting-induced decrease of neuronal nitric oxide synthase (nNOS) in the magnocellular division of the paraventricular nucleus (PVN). Rats were...
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Adrenalectomy Abolishes Fasting-induced Down-regulation of NADPH-diaphorase in the Rat Paraventricular Nucleus

Jahng JW, Lee JH, Kim GT, Kim YM, Houpt TA, Kim DG

This study was conducted to define the molecular mechanism of fasting-induced down-regulation of neuronal nitric oxide synthase (nNOS) expression in the hypothalamic paraventricular nucleus (PVN). Rats were adrenalectomized (ADX), and...
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Subdiaphragmatic vagotomy induces NADPH diaphorase in the rat dorsal motor nucleus of the vagus

Jahng JW, Kim DG, Houpt TA

Axotomy of the vagal motor neurons by cervical vagotomy induces NADPH diaphorase staining due to increased nitric oxide synthase expression in both the rat dorsal motor nucleus...
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The distribution of nitric oxide synthase in human corpus cavernosum on various impotent patients

Choi YD, Mah SY, Xin ZC, Choi HK

Recent evidence implicates NO (Nitric oxide) as the principal mediator in an erection. To investigate the role of NO in the human erectile function, we studied the distribution...
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Correlation of Functional Changes on Bladder and Proximal Urethra with Neuronal Nitric Oxide Synthase in Pelvic Ganglion Denervated Rats

Kim JW, Jung HC, Park TC

  • KMID: 1914280
  • Korean J Urol.
  • 1997 Dec;38(12):1275-1282.
Injuries to the pelvic nerve plexus following major pelvic ablative surgery are commonly observed conditions in urologic field and often related to voiding difficulty with flaccid type of neurogenic bladder....
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Correlation of Neuronal Nitric Oxide Synthase with Penile Erection in Diabetic Rats

Moon KH, Jung HC, Park TC, Lee YC, Huh K, Park JM, Suh JK

  • KMID: 2060719
  • Korean J Urol.
  • 1997 Jun;38(6):575-584.
Diabetes mellitus (DM) is an important cause of organic impotence in man. The exact pathogenesis remains debatable although it has been focused on cavernosal neuropathy and/or endothelial dysfunction. This study...
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Role of Nitric Oxide and Nitric Oxide Synthase in Penile Erection

Jung HC, Suh JK, Park TC

  • KMID: 2290037
  • Korean J Urol.
  • 1996 Apr;37(4):361-370.
Nitric oxide(NO) is known to act as an important neural mediator of penile erection. Nitric oxide synthase(NOS), which produces NO, has been recently identified in autonomic neurons supplying genitourinary organs...
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Effect of Testosterone Replacement on Penile Erection in Castrated Rat

Lee HB, Sohn DW, Im JG, Lee CB, Kang SH, Kim SW, Cho YH, Yoon MS

  • KMID: 2226653
  • Korean J Androl.
  • 2005 Aug;23(2):94-99.
PURPOSE: This study examined the changes in intracavernous pressure, expression of nitric oxide synthase(NOS), and content of penile smooth muscle in castrated rats and testosterone-supplied castrated rats. MATERIALS AND METHODS: Sprague...
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Nitroxergic nerve relaxes rat gastric smooth muscle by NO-cGMP pathway

Yoon YS, Choi HC, Jung YS, Kim JH, Lee KY, Sohn UD, Ha JH, Kim WJ

  • KMID: 1580934
  • Korean J Physiol Pharmacol.
  • 2000 Oct;4(5):369-378.
This study was undertaken to investigate an involvement of nitroxergic innervation in gastric smooth muscle of rat. Isometric tension study, the measurement of single cell length, NADPH diaphorase stain of smooth muscle layers...
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Alteration of nitrergic neuromuscular transmission as a result of acute experimental colitis in rat

Sung TS, La JH, Kim TW, Yang IS

Nitric oxide (NO) is a non-adrenergic, non-cholinergic neurotransmitter found in the enteric nervous system that plays a role in a variety of enteropathies, including inflammatory bowel disease. Alteration of nitrergic neurons has been reported...
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