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Characterization of pncA Mutations of Pyrazinamide-Resistant Mycobacterium tuberculosis in Korea

Lee KW, Lee JM, Jung KS

Pyrazinamide (PZA) is one of the most important drugs for the treatment of Mycobacterium tuberculosis infection. However, the increasing frequency of PZA-resistant strains limits its effectiveness. In Korea, most PZA-resistant...
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Detection of Rifampin Resistant Mycobacterium tuberculosis complex using Denaturing HPLC

Nam YH, Lee SH, Ahn YC, Cho MH, Jang WC, Park SM, Kwon PS, Kim JW

BACKGROUND: Tuberculosis (TB) remains an important cause of morbidity and mortality throughout the world. The surge of TB has been accompanied by an increase in multi-drug-resistant tuberculosis (MDR-TB). In...
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Mutations in the embB Locus among Korean Clinical Isolates of Mycobacterium tuberculosis Resistant to Ethambutol

Lee HY, Myoung HJ, Bang HE, Bai GH, Kim SJ, Kim JD, Cho SN

Resistance of Mycobacterium tuberculosis to ethambutol (EMB) has been assigned to an operon, embCAB, which has been proposed to be a structural gene for mycobacterial arabinosyl transferases. Recently, genetic events...
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