- Genetic screening in young women diagnosed with endometrial cancer
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Pecorino B, Rubino C, Guardalà FVF, Galia A, Scollo P
- KMID: 2413851
- J Gynecol Oncol.
- 2017 Jan;28(1):e4.
- doi: 10.3802/jgo.2017.28.e4
OBJECTIVE: To evaluate the importance of Lynch syndrome associated risk screening in the patients aged less than 50 years affected from endometrial cancer. METHODS: From 2007 to 2014, 41 patients affected... -
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- DNA mismatch repair-related protein loss as a prognostic factor in endometrial cancers
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Kato M, Takano M, Miyamoto M, Sasaki N, Goto T, Tsuda H, Furuya K
- KMID: 2158801
- J Gynecol Oncol.
- 2015 Jan;26(1):40-45.
- doi: 10.3802/jgo.2015.26.1.40
OBJECTIVE: Recent investigations have revealed DNA mismatch repair (MMR) gene mutations are closely related with carcinogenesis of endometrial cancer; however the impact of MMR protein expression on prognosis is not... -
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- Is Immunohistochemistry for MLH1 and MSH2 Proteins a Useful Method for Detection of Microsatellite Instability in Sporadic Colorectal Cancer?
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Do JH, Chang SK, Ahnn JY, Cha BK, Cheong SM, Kim DW, Cheong HR, Kim HJ, Kim JG, Lee TJ, Park ES, Park SM
- KMID: 1112187
- Korean J Gastroenterol.
- 2003 Nov;42(5):369-376.
BACKGROUND/AIMS: In order to identify microsatellite instability (MSI), the test based on the polymerase chain reaction (PCR) can be used. However, PCR is not routinely performed in all hospital... -
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- Clinicopathological Characteristics of Colorectal Cancer with Family History: an Evaluation of Family History as a Predictive Factor for Microsatellite Instability
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Park IJ, Kim HC, Yoon YS, Yu CS, Jang SJ, Kim JC
- KMID: 1785795
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S91-S97.
- doi: 10.3346/jkms.2007.22.S.S91
To determine whether family history of cancer may be a risk factor for the mutator phenotype in colorectal cancer, we recruited 143 consecutive colorectal cancer patients with a family history... -
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- Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-beta in colorectal cells
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He YQ, Sheng JQ, Ling XL, Fu L, Jin P, Yen L, Rao J
- KMID: 1402316
- Exp Mol Med.
- 2012 Dec;44(12):723-732.
Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors.... -
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