- Intrathecal Lamotrigine Attenuates Antinociceptive Morphine Tolerance and Suppresses Spinal Glial Cell Activation in Morphine-Tolerant Rats
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Jun IG, Kim SH, Yoon YI, Park JY
- KMID: 1429208
- J Korean Med Sci.
- 2013 Feb;28(2):300-307.
- doi: 10.3346/jkms.2013.28.2.300
Glial cells play a critical role in morphine tolerance, resulting from repeated administration of morphine. Both the development and the expression of tolerance are suppressed by the analgesic lamotrigine. This... -
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- Tocolytic Effect of Morphine via Increased Metabolic Clearance of Oxytocin in the Baboon
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Bai YH, Pak SC, Choi BC, Wilson L
- KMID: 1728848
- Yonsei Med J.
- 2002 Oct;43(5):567-572.
- doi: 10.3349/ymj.2002.43.5.567
Morphine is known to inhibit nocturnal uterine contractions in several animal models, and oxytocin is known to be a primary causative factor of uterine contractions. The purpose of the present... -
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- Effects of MK-801 and Morphine on Spinal C-Fos Expression during the Development of Neuropathic Pain
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Lee YW, Park KA, Lee WT
- KMID: 1105109
- Yonsei Med J.
- 2002 Jun;43(3):370-376.
- doi: 10.3349/ymj.2002.43.3.370
The purpose of this study was to investigate the expression of c-fos in the spinal cord during the development of allodynia, induced by peripheral nerve injury. Following tight ligation of... -
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- Morphine Postconditioning Attenuates ICAM-1 Expression on Endothelial Cells
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Min TJ, Kim JI, Kim JH, Noh KH, Kim TW, Kim WY, Lee YS, Park YC
- KMID: 1782121
- J Korean Med Sci.
- 2011 Feb;26(2):290-296.
- doi: 10.3346/jkms.2011.26.2.290
The purpose of this study is to determine 1) whether morphine postconditiong (MPostC) can attenuate the intercellular adhesion molecules-1 (ICAM-1) expression after reoxygenation injury and 2) the subtype(s) of the... -
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- Morphine Attenuates Endothelial Cell Adhesion Molecules Induced by the Supernatant of LPS-Stimulated Colon Cancer Cells
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Min TJ, Park SH, Ji YH, Lee YS, Kim TW, Kim JH, Kim WY, Park YC
- KMID: 1785959
- J Korean Med Sci.
- 2011 Jun;26(6):747-752.
- doi: 10.3346/jkms.2011.26.6.747
A large reservoir of bacterial lipopolysaccharide (LPS) is available in the colon and this could promote colon cancer metastasis by enhancing tumor cell adhesion, intravasation, and extravasation. Furthermore, adhesion molecules... -
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