- Special issue on neurodegenerative diseases and their therapeutic approaches
-
Kim J, Mook-Jung
- KMID: 2155411
- Exp Mol Med.
- 2015 Mar;47(3):e146.
- doi: 10.1038/emm.2015.13
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- The role of mitochondrial DNA mutation on neurodegenerative diseases
-
Cha MY, Kim DK, Mook-Jung
- KMID: 2155415
- Exp Mol Med.
- 2015 Mar;47(3):e150.
- doi: 10.1038/emm.2014.122
Many researchers have reported that oxidative damage to mitochondrial DNA (mtDNA) is increased in several age-related disorders. Damage to mitochondrial constituents and mtDNA can generate additional mitochondrial dysfunction that may... -
- CITED
-
- Close
- SHARE
-
- Close
- Diverse Molecular Targets for Therapeutic Strategies in Alzheimer's Disease
-
Han SH, Mook-Jung
- KMID: 1789947
- J Korean Med Sci.
- 2014 Jul;29(7):893-902.
- doi: 10.3346/jkms.2014.29.7.893
Alzheimer's disease (AD) is the most common form of dementia caused by neurodegenerative process and is tightly related to amyloid beta (Abeta) and neurofibrillary tangles. The lack of early diagnostic... -
- CITED
-
- Close
- SHARE
-
- Close
- Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice
-
Jeon SG, Kang M, Kim YS, Kim DH, Nam DW, Song EJ, Mook-Jung , Moon M
- KMID: 2440056
- Exp Mol Med.
- 2018 Mar;50(3):e461.
- doi: 10.1038/emm.2017.302
Progressive cognitive declines are the main clinical symptoms of Alzheimer’s disease (AD). Cognitive impairment in AD is directly correlated with amyloid beta (Aβ)-mediated synaptic deficits. It is known that upregulation... -
- CITED
-
- Close
- SHARE
-
- Close
- Caveolin-1 upregulation in senescent neurons alters amyloid precursor protein processing
-
Kang MJ, Chung YH, Hwang CI, Murata M, Fujimoto T, Mook-Jung , Cha CI, Park WY
- KMID: 1111405
- Exp Mol Med.
- 2006 Apr;38(2):126-133.
Lipid rafts provide a platform for regulating cellular functions and participate in the pathogenesis of several diseases. However, the role of caveolin-1 in this process has not been elucidated definitely... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Ischemic Neuronal Insults on Amyloid Precursor Protein Processing
-
Lee PH, Hwang EM, Mook-Jung , Huh K, Choi IS
- KMID: 2343147
- J Korean Neurol Assoc.
- 2005 Apr;23(2):241-248.
BACKGROUND: In spite of the different pathogenesis and exclusive respect in the diagnosis of Alzheimer's disease (AD) and vascular dementia (VaD), recent epidemiological and pathological studies indicates that ischemic stroke... -
- CITED
-
- Close
- SHARE
-
- Close
- Synapsin-1 and tau reciprocal O-GlcNAcylation and phosphorylation sites in mouse brain synaptosomes
-
Kang MJ, Kim C, Jeong H, Cho BK, Ryou AL, Hwang D, Mook-Jung , Yi EC
- KMID: 2154248
- Exp Mol Med.
- 2013 Jun;45(6):e29.
O-linked N-acetylglucosamine (O-GlcNAc) represents a key regulatory post-translational modification (PTM) that is reversible and often reciprocal with phosphorylation of serine and threonine at the same or nearby residues. Although recent... -
- CITED
-
- Close
- SHARE
-
- Close
- Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease: Methodology and Baseline Sample Characteristics
-
Byun MS, Yi D, Lee JH, Choe YM, Sohn BK, Lee JY, Choi HJ, Baek H, Kim YK, Lee YS, Sohn CH, Mook-Jung , Choi M, Lee YJ, Lee DW, Ryu SH, Kim SG, Kim JW, Woo JI, Lee DY, KBASE Research Group
- KMID: 2402414
- Psychiatry Investig.
- 2017 Nov;14(6):851-863.
- doi: 10.4306/pi.2017.14.6.851
OBJECTIVE: The Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's disease (KBASE) aimed to recruit 650 individuals, aged from 20 to 90 years, to search for... -
- CITED
-
- Close
- SHARE
-
- Close
