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Role of intracellular taurine in monensin-induced Na+, Ca++ accumulation and mechanical dysfunction in isolated rat hearts

Kim YH, Park JW, Kim MS

  • KMID: 1554764
  • Korean J Physiol Pharmacol.
  • 1997 Oct;1(5):537-546.
It has been postulated that the intracellular taurine is co-transported with Na+ down a concentration gradient and prevents the intracellular accumulation of sodium. It is therefore, expected that an elevated level of intracellular...
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Autophagy Inhibition with Monensin Enhances Cell Cycle Arrest and Apoptosis Induced by mTOR or Epidermal Growth Factor Receptor Inhibitors in Lung Cancer Cells

Choi HS, Jeong EH, Lee TG, Kim SY, Kim HR, Kim CH

  • KMID: 2320432
  • Tuberc Respir Dis.
  • 2013 Jul;75(1):9-17.
BACKGROUND: In cancer cells, autophagy is generally induced as a pro-survival mechanism in response to treatment-associated genotoxic and metabolic stress. Thus, concurrent autophagy inhibition can be expected to have a...
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Roles of Na+-Ca2+ exchange in the negative force-frequency relationship

Ko CM, Kim SJ

  • KMID: 2071830
  • Korean J Physiol Pharmacol.
  • 1998 Dec;2(6):715-724.
Frequency-force relationships (FFR) were studied in electrically field stimulated rat left atria (LA) by reducing the stimulation frequency from resting 3 Hz to test frequencies (0.1-1 Hz) for 5 minutes. The twitch amplitudes...
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Comparison of the determinants in the differences in force-frequency relationships between rat and rabbit left atria

Ko CM, Kim SJ

  • KMID: 1580940
  • Korean J Physiol Pharmacol.
  • 2000 Oct;4(5):417-425.
The underlying mechanism commonly applicable for both the positive and negative force-frequency relationships (FFR) was pursued in left atria (LA) of rat and rabbit. The species differences in the roles of Na+/Ca2+ exchanger...
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Studies on the roles of Na+/-Ca2+ exchange according to postnatal age in the negative staircase effect of the rat heart

Lee HY, Kim SJ, Ko CM

  • KMID: 2285189
  • Korean J Physiol Pharmacol.
  • 1997 Dec;1(6):707-716.
Recent reports revealed that the Na+/-Ca2+ exchangers and feet structures of sarcoplasmic reticulum (SR) are located in close vicinity in the specific compartment. Therefore, we investigated the possibility that the Na+/-Ca2+ exchanger may...
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Effects of intracellular sodium concentration on the bone resorption in organ culture

Lee TJ, Yang WS

  • KMID: 2271467
  • Korean J Orthod.
  • 1989 Mar;19(1):61-75.
Recently, indirect evidences suggest that Na-Ca exchange mechanism is involved in bone resorption. To study this suggestion, effects of several drugs which increase the intracellular sodium concentration by different mechanisms...
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