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Comparison between Immunostimulatory Activity and Molecular Structure of Different Polysaccharides

Shim JY, Jung IS, Kim CW, Yun YS, Song JY

BACKGROUND: We previously reported that ginsan, a polysaccharide extracted from Panax ginseng had an immunostimulatory activity such as mitogenic activity, activation of macrophages and killer cells, and production of a...
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General properties and phylogenetic utilities of nuclear ribosomal DNA and mitochondrial DNA commonly used in molecular systematics

Hwang UW, Kim W

To choose one or more appropriate molecular markers or gene regions for resolving a particular systematic question among the organisms at a certain categorical level is still a very...
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The Molecular Structures and Function of the Yeast Saccharomyces cerevisiae Cell Wall

Chang MS, Kim SC, Choi SH, Woo JH

  • KMID: 1513553
  • Korean J Med Mycol.
  • 2007 Sep;12(3):129-138.
The main characteristics of molecular structures of the yeast Saccharomyces cerevisiae cell wall are now elucidated. The cell wall of Saccharomyces cerevisiae is composed of inner layer and outer layer...
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Biochemical Characteristics of Dysfunctional Fibrinogen Found in Korea

Kim I, Park S, Kwon S, Chung I, Lee S

BACKGROUND: Hereditary dysfibrinogenemia is a rare cause of venous thromboembolism. Hereditary thrombophilia is diagnosed in about 10% of patients with thromboembolism, with the prevalence diagnosed increasing with the development of...
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Isolation and Partial Characterization of a 50 kDa Hemin-regulated Cell Envelope Protein from Prevotella nigrescens

Kim KM, Choi JI, Kim SJ

In the study presented here, identification, purification, and partial characterization of a hemin-regulated protein in Prevotella nigrescens were carried out. The results of this study confirm that the availability of...
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Cholesterol induce oligomerization of Vibrio vulnificus cytolysin specifically.

Kim BS, Kim JS

  • KMID: 1380232
  • Exp Mol Med.
  • 2002 Jul;34(3):239-242.
Vibrio vulnificus cytolysin (VVC) has been implicated as one of the important virulence determinants of V. vulnificus that causes serious septicemia and wound infection. An attempt was made to investigate...
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Alteration of Nerve Growth Factor in the Penis of Rats with Streptozotocin-induced Diabetes

Cho JS, Ryu I, Kim KA, Lee SK, Park YE

  • KMID: 2060550
  • Korean J Urol.
  • 1995 Jan;36(1):23-27.
Insulin and nerve growth factor (NGF) share several properties concerning physiological activity, molecular structure and site of synthesis. Considering the properties that NGF shares with insulin, and the important role...
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Isolation and Partial Characterization of Hemin-binding Cell Envelope Proteins from Porphyromonas gingivalis, Prevotella intermedia, and Prevotella nigrescens

Kim SJ

  • KMID: 2462858
  • J Korean Acad Periodontol.
  • 2006 Mar;36(1):155-165.
The results of this study confirm that the availability of hemin influences the expression of selected membrane proteins of Porphyromonas gingivalis, Prevotella intermedia, and Prevotella nigrescens. A 30 kDa (heated...
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Intestinal Permeability Regulation by Tight Junction: Implication on Inflammatory Bowel Diseases

Lee SH

Epithelial tight junctions (TJs) are the key structures regulating paracellular trafficking of macromolecules. The TJ is multi-protein complex that forms a selective permeable seal between adjacent epithelial cells and demarcates...
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Chromatin Pattern-Dependent mRNA Synthesis in HeLa Cells and HeLa Tumors

Lee JH, Kang MW, Choi C, Juhng SW

  • KMID: 2172398
  • Chonnam Med J.
  • 2001 Dec;37(4):351-356.
Malignant cell nuclei, in general, have increased amount of heterochromatin and decreased electron density of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. Chromatin pattern in...
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mRNA is Synthesized Mainly at the Phase between the Euchromatin and Heterochromatin: Proposal of a Phase Theory

Kim MS, Juhng SW

  • KMID: 2275638
  • Korean J Pathol.
  • 2001 Apr;35(2):93-97.
BACKGROUND: Malignant cell nuclei, in general, have increased amounts of heterochromatin and decreased electron densities of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. The...
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Biological effects of fucoidan isolated from Fucus vesiculosus on thrombosis and vascular cells

Kwak KW, Cho KS, Hahn OJ, Lee KH, Lee BY, Ko JJ, Chung KH

BACKGROUND: Fucoidan is a highly sulfated glycosaminoglycan, which has a molecular structure similar to that of heparin. The antithrombotic effects of fucoidan in vitro have been widely reported, but its...
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Analysis of Normal and Cancer Tissue in the Stomach Using Raman Spectroscopy

Lee SH, Seo KW, Lee SH, Jeon TY, Sim MS, Kim HH, Lee S, Jeong ED

  • KMID: 2145097
  • J Korean Surg Soc.
  • 2005 Aug;69(2):113-119.
PURPOSE: Raman spectroscopy is a vibrational spectroscopic technique, which is capable of providing details on the chemical composition, molecular structure and molecular interactions in cells and tissues. The primary objective...
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Eukaryotic Kxpression of the Major Antigenic Determinants Evoking Neutralizing Antibodies in Human Cytomegalovirus ( HCMV ) Isolated in Korea

Park CG, Kook YH, Cha CY, Hwang ES, Lim DG, Park JW

  • KMID: 1540527
  • J Korean Soc Microbiol.
  • 1997 Jun;32(3):315-324.
Human cytomegalovirus (HCMV) isolated from Korean patients is different in the antigenic and genomic structure of gB from the laboratory-adapted strain. To dissect the reactivity to HCMV glycoprotein B (gB)...
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Psammaplin A is a natural prodrug that inhibits class I histone deacetylase

Kim DH, Shin J, Kwon HJ

  • KMID: 1103680
  • Exp Mol Med.
  • 2007 Feb;39(1):47-55.
Histone deacetylase (HDAC) has been highlighted as one of key players in tumorigenesis and angiogenesis. Recently, several derivatives of psammaplin (Psams) from a marine sponge have been known to inhibit...
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Effects of Potassium Channel Modulators on Contractile Responses of Isolated Rat Vas Deferens to Field Stimulation

Baik YH, Kim YM, Rhu BS

  • KMID: 1973325
  • Chonnam Med J.
  • 2002 Mar;38(1):17-23.
Apart from regulating the resting membrane potential, K+ channels might also participate in cellular activity in response to endogenous neurotransmitters and exogenous agents. K+ channel modulators including 4 - aminopyridine...
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Simultaneous Determination of Various Macrolides by Liquid Chromatography/Mass Spectrometry

Hwang YH, Lim JH, Park BK, Yun HI

  • KMID: 1095368
  • J Vet Sci.
  • 2002 Jun;3(2):103-108.
Macrolides are frequently used in veterinary medicine as therapeutic and preventive agents for various diseases. It is difficult to determine macrolides simultaneously with conventional methods due to their similar structures....
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The Expression of Elafin and Its Implication in the Inflammatory and Keratinizing Disorders of the Skin

Kim CH, Kim SN, Song HJ

  • KMID: 2146465
  • Korean J Dermatol.
  • 2000 Dec;38(12):1603-1614.
BACKGROUND: Elafin is a serine proteinase inhibitor first discovered in keratinocytes from psoriatic epidermis. The molecular structure of elafin contains two different functional domains; one for the proteinase inhibitor, which...
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Elevated Levels of Proinflammatory Cytokines Interleukin-1beta, Interleukin-6, and Tumor Necrosis Factor-alpha in Rats after Kainic Acid-induced Seizures

Lim KI, Kim KS, Lee JH, Kim MJ, Kim JK, Yoo BG

  • KMID: 1816505
  • J Korean Epilepsy Soc.
  • 2006 Jun;10(1):18-23.
PURPOSE: The cerebral inflammatory reactions accompanied with epilepsy could play a role in intervening the possible changes of cerebral molecular structure during or after seizure. This study was intended to...
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Diagnosis and Treatment of Cough

Kim YC

Cough remains the most common reason for patients to seek medical attention. Although the exact prevalence is difficult to estimate, recurrent cough is reported in up to 40% of the...
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