- Mitochondrial Permeability Transition Pore and Cardioprotection Against Ischemia-reperfusion Injury
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Lee JW, Shim YH
- KMID: 2188082
- J Korean Med Assoc.
- 2009 Oct;52(10):1007-1019.
- doi: 10.5124/jkma.2009.52.10.1007
Opening of mitochondrial permeability transition pore (mPTP) was found to have a critical role in cell death from ischemia/reperfusion (I/R) injury experimentally in the late 1980's. Thereafter, tremendous efforts have... -
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- Protective Effect of PGC-1 on Lipid Overload-induced Apoptosis in Vascular Endothelial Cell
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Koh EH, Kim YM, Kim HJ, Lee WJ, Won JC, Kim MS, Lee KU, Park JY
- KMID: 2177606
- J Korean Diabetes Assoc.
- 2006 May;30(3):151-160.
- doi: 10.4093/jkda.2006.30.3.151
BACKGROUND: Fatty acids contribute to endothelial cell dysfunction and apoptosis by inducing accumulation of long chain fatty acyl CoA (LCAC), which increases oxidative stress in vascular endothelial cells. Forced expression... -
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- ANT2 shRNA downregulates miR-19a and miR-96 through the PI3K/Akt pathway and suppresses tumor growth in hepatocellular carcinoma cells
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Baik SH, Lee J, Lee YS, Jang JY, Kim CW
- KMID: 2361509
- Exp Mol Med.
- 2016 Mar;48(3):e222.
- doi: 10.1038/emm.2015.126
MicroRNAs (miRNAs) are negative regulators of gene expression, and miRNA deregulation is found in various tumors. We previously reported that suppression of adenine nucleotide translocase 2 (ANT2) by short hairpin... -
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