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Efficacy of low-dose spironolactone on top of angiotensin receptor blockade in patients with glomerulonephritis

Yu BC, Lee MS, Moon JJ, Choi SJ, Kim JK, Hwang SD, Park MY

BACKGROUND: Previous studies have shown that aldosterone antagonists have a proteinuria-lowering effect in patients with proteinuria and progressive proteinuric disease not adequately controlled by the use of angiotensin receptor blockers...
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Role of the renin-angiotensin system in hepatic fibrosis and portal hypertension

Shim KY, Eom YW, Kim MY, Kang SH, Baik SK

The renin-angiotensin system (RAS) is an important regulator of cirrhosis and portal hypertension. As hepatic fibrosis progresses, levels of the RAS components angiotensin (Ang) II, Ang-(1–7), angiotensin-converting enzyme (ACE), and...
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Post-transplant Proteinuria

Choi KH

  • KMID: 2201848
  • J Korean Soc Transplant.
  • 2007 Jun;21(1):22-30.
Proteinuria is a cardinal manifestation of renal disease and has been proposed to promote progression of renal disease. Proteinuria develops in 9~41% of transplant recipients, and is diagnosed by routine...
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Effect of Eplerenone, a Selective Aldosterone Blocker, on the Development of Diabetic Nephropathy in Type 2 Diabetic Rats

Ahn JH, Hong HC, Cho MJ, Kim YJ, Choi HY, Eun CR, Yang SJ, Yoo HJ, Kim HY, Seo JA, Kim SG, Choi KM, Baik SH, Choi DS, Kim NH

BACKGROUND: Aldosterone antagonists are reported to have beneficial effects on diabetic nephropathy by effective blocking of the renin-angiotensin-aldosterone system. We investigated the renoprotective effect of the selective aldosterone receptor blocker...
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Clinical Characteristics and Outcome of Acute Heart Failure in Korea: Results from the Korean Acute Heart Failure Registry (KorAHF)

Lee SE, Lee HY, Cho HJ, Choe WS, Kim H, Choi JO, Jeon ES, Kim MS, Kim JJ, Hwang KK, Chae SC, Baek SH, Kang SM, Choi DJ, Yoo BS, Kim KH, Park HY, Cho MC, Oh BH

BACKGROUND AND OBJECTIVES: The burden of heart failure has increased in Korea. This registry aims to evaluate demographics, clinical characteristics, management, and long-term outcomes in patients hospitalized for acute heart...
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