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Evaluations of Gastric Acid Pocket Using Novel Vertical 8-Channel pH Monitoring System and Effects of Acid Secretion Inhibitors

Sumi S, Ishimura N, Mikami H, Okimoto E, Tamagawa Y, Mishiro T, Kinoshita Y, Ishihara S

  • KMID: 2517531
  • J Neurogastroenterol Motil.
  • 2021 Jul;27(3):370-376.
  • doi: 10.5056/jnm20115
Background/Aims The gastric acid pocket has an important role in gastroesophageal reflux disease development. In this study, we utilized a novel 8-channel pH monitoring system with sensor intervals of 1 cm...
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Acotiamide Has No Effects on Esophageal Motor Activity or Esophagogastric Junction Compliance

Mikami H, Ishimura N, Okada M, Izumi D, Okimoto E, Ishihara S, Kinoshita

  • KMID: 2413100
  • J Neurogastroenterol Motil.
  • 2018 Apr;24(2):241-247.
  • doi: 10.5056/jnm16111
BACKGROUND/AIMS: The novel prokinetic drug acotiamide is used for treatment of functional dyspepsia. It is still unclear how acotiamide has effects on esophageal motor function. Esophageal peristalsis and esophagogastric junction...
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Effects of Metoclopramide on Esophageal Motor Activity and Esophagogastric Junction Compliance in Healthy Volunteers

Mikami H, Ishimura N, Fukazawa K, Okada M, Izumi D, Shimura S, Okimoto E, Aimi M, Ishihara S, Kinoshita

  • KMID: 2379710
  • J Neurogastroenterol Motil.
  • 2016 Jan;22(1):112-117.
  • doi: 10.5056/jnm15130
BACKGROUND/AIMS: Prokinetic drugs such as metoclopramide are frequently used as second-line therapy for patients with gastroesophageal reflux disease. However, their beneficial effects remain unclear. Esophageal motor activities and compliance of...
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Small Intestinal Bacterial Overgrowth in Patients with Refractory Functional Gastrointestinal Disorders

Shimura S, Ishimura N, Mikami H, Okimoto E, Uno G, Tamagawa Y, Aimi M, Oshima N, Sato S, Ishihara S, Kinoshita

  • KMID: 2379704
  • J Neurogastroenterol Motil.
  • 2016 Jan;22(1):60-68.
  • doi: 10.5056/jnm15116
BACKGROUND/AIMS: Small intestinal bacterial overgrowth (SIBO) is considered to be involved in the pathogenesis of functional gastrointestinal disorders (FGID). However, the prevalence and clinical conditions of SIBO in patients with...
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