- Interleukin-10 endogenously expressed in microglia prevents lipopolysaccharide-induced neurodegeneration in the rat cerebral cortex in vivo
-
Park KW, Lee HG, Jin BK, Lee YB
- KMID: 1091076
- Exp Mol Med.
- 2007 Dec;39(6):812-819.
A degree of brain inflammation is required for repair of damaged tissue, but excessive inflammation causes neuronal cell death. Here, we observe that IL-10 is expressed in LPS-injected rat cerebral... -
- CITED
-
- Close
- SHARE
-
- Close
- Intrathecal Lamotrigine Attenuates Antinociceptive Morphine Tolerance and Suppresses Spinal Glial Cell Activation in Morphine-Tolerant Rats
-
Jun IG, Kim SH, Yoon YI, Park JY
- KMID: 1429208
- J Korean Med Sci.
- 2013 Feb;28(2):300-307.
- doi: 10.3346/jkms.2013.28.2.300
Glial cells play a critical role in morphine tolerance, resulting from repeated administration of morphine. Both the development and the expression of tolerance are suppressed by the analgesic lamotrigine. This... -
- CITED
-
- Close
- SHARE
-
- Close
- Activation of nicotinic acetylcholine receptor prevents the production of reactive oxygen species in fibrillar beta amyloid peptide (1-42)-stimulated microglia
-
Moon JH, Kim SY, Lee HG, Kim SU, Lee YB
- KMID: 1103583
- Exp Mol Med.
- 2008 Feb;40(1):11-18.
- doi: 10.3858/emm.2008.40.1.11
Recent studies have reported that the "cholinergic anti-inflammatory pathway" regulates peripheral inflammatory responses via alpha7 nicotinic acetylcholine receptors (alpha7 nAChRs) and that acetylcholine and nicotine regulate the expression of proinflammatory... -
- CITED
-
- Close
- SHARE
-
- Close
- Naegleria fowleri Lysate Induces Strong Cytopathic Effects and Pro-inflammatory Cytokine Release in Rat Microglial Cells
-
Lee YJ, Park CE, Kim JH, Sohn HJ, Lee J, Jung SY, Shin HJ
- KMID: 1715653
- Korean J Parasitol.
- 2011 Sep;49(3):285-290.
- doi: 10.3347/kjp.2011.49.3.285
Naegleria fowleri, a ubiquitous free-living ameba, causes fatal primary amebic meningoencephalitis in humans. N. fowleri trophozoites are known to induce cytopathic changes upon contact with microglial cells, including necrotic and... -
- CITED
-
- Close
- SHARE
-
- Close
- Cell type-specific upregulation of myristoylated alanine-rich C kinase substrate and protein kinase C-alpha, -beta I, -beta II, and -delta in microglia following kainic acid-induced seizures
-
Eun SY, Kim EH, Kang KS, Kim HJ, Jo SA, Kim SJ, Jo SH, Kim SJ, Blackshear PJ, Kim J
- KMID: 1094157
- Exp Mol Med.
- 2006 Jun;38(3):310-319.
Myristoylated alanine-rich C kinase substrate (MARCKS) is a widely distributed protein kinase C (PKC) substrate and has been implicated in actin cytoskeletal rearrangement in response to extracellular stimuli. Although MARCKS... -
- CITED
-
- Close
- SHARE
-
- Close
- Upregulation of Proinflammatory Cytokines in the Fetal Brain of the Gaucher Mouse
-
Hong YB, Kim EY, Jung SC
- KMID: 2157830
- J Korean Med Sci.
- 2006 Aug;21(4):733-738.
- doi: 10.3346/jkms.2006.21.4.733
Gaucher disease is caused by a deficiency of glucocerebrosidase. Patients with Gaucher disease are divided into three major phenotypes: chronic nonneuronopathic, acute neuronopathic, and chronic neuronopathic, based on symptoms of... -
- CITED
-
- Close
- SHARE
-
- Close
