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A Case of Crohn's Disease Showing Favorable Response to Induction and Maintenance Therapy with Methotrexate after Failure of Anti-tumor Necrosis Factor Therapy

Choi J, Yun GW, Park YM, Kim JH, Youn YH, Park H, Park JJ

Thanks to the introduction of immumomodulators and biologics, therapeutic approaches in Crohn's disease have changed significantly during the past decade. Although new biologic therapy has dramatically improved the treatment of...
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A Clinical Trial and Extension Study of Infliximab in Korean Patients with Active Rheumatoid Arthritis despite Methotrexate Treatment

Kim J, Ryu H, Yoo DH, Park SH, Song GG, Park W, Cho CS, Song YW

Currently, infliximab is given for disease control for active rheumatoid arthritis (RA) patients despite methotrexate treatment. However, the efficacy and safety of infliximab in Korean patients has not been assessed...
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Oral Maintenance Chemotherapy with 6-Mercaptopurine and Methotrexate in Patients with Acute Myeloid Leukemia Ineligible for Transplantation

Choi YW, Jeong SH, Ahn MS, Lee HW, Kang SY, Choi JH, Park JS

For decades, maintenance chemotherapy has failed to improve the cure rate or prolong the survival of patients with acute myeloid leukemia (AML), other than those with acute promyelocytic leukemia. Immediately...
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Effects of Methotrexate on Carotid Intima-media Thickness in Patients with Rheumatoid Arthritis

Kim HJ, Kim MJ, Lee CK, Hong YH

The purpose of this study was to evaluate the effects of rheumatoid arthritis (RA) and antirheumatic drugs on atherosclerosis by comparing carotid intima-media thickness (CIMT) as an indicator for cardiovascular...
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A Case of Intravenous Immunoglobulin-Resistant Kawasaki Disease Treated with Methotrexate

Lee MS, An SY, Jang GC, Kim DS

Kawasaki disease, an acute febrile vasculitis of unknown etiology, is usually treated with high doses of immunoglobulin (IVIG) and aspirin. However, 20% of children show persistent or recurrent fever despite...
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