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Slow Transit Constipation Associated With Excess Methane Production and Its Improvement Following Rifaximin Therapy: A Case Report

Ghoshal UC, Srivastava D, Verma A, Misra A

  • KMID: 2326214
  • J Neurogastroenterol Motil.
  • 2011 Apr;17(2):185-188.
Constipation, a common problem in gastroenterology practice, may result from slow colonic transit. Therapeutic options for slow transit constipations are limited. Excessive methane production by the methanogenic gut flora, which...
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Unreliability of Breath Methane as a Candidate Indicator of Functional Bowel Disorders

Jonderko K, Gabriel-Jasniok A, Szymszal M, Kasicka-Jonderko A, Blonska-Fajfrowska B

  • KMID: 2053360
  • Gut Liver.
  • 2008 Dec;2(3):180-185.
BACKGROUND/AIMS: The aim of this study was to examine the reproducibility of methane and hydrogen in exhaled air breath after a per-oral load of lactulose. METHODS: Methane was present in the...
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Methanogens, Methane and Gastrointestinal Motility

Triantafyllou K, Chang C, Pimentel M

  • KMID: 2381147
  • J Neurogastroenterol Motil.
  • 2014 Jan;20(1):31-40.
Anaerobic fermentation of the undigested polysaccharide fraction of carbohydrates produces hydrogen in the intestine which is the substrate for methane production by intestinal methanogens. Hydrogen and methane are excreted in...
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Acute Respiratory Distress Due to Methane Inhalation

Jo JY, Kwon YS, Lee JW, Park JS, Rho BH, Choi WI

  • KMID: 2320349
  • Tuberc Respir Dis.
  • 2013 Mar;74(3):120-123.
Inhalation of toxic gases can lead to pneumonitis. It has been known that methane gas intoxication causes loss of consciousness or asphyxia. There is, however, a paucity of information about...
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Association between Symptoms of Irritable Bowel Syndrome and Methane and Hydrogen on Lactulose Breath Test

Lee KN, Lee OY, Koh DH, Sohn W, Lee SP, Jun DW, Lee HL, Yoon BC, Choi HS, Hahm JS

Whether hydrogen and methane gas produced during lactulose breath test (LBT) are associated with symptoms of irritable bowel syndrome (IBS) is not determined. We aimed to investigate whether hydrogen and...
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Irritable Bowel Syndrome, Particularly the Constipation-Predominant Form, Involves an Increase in Methanobrevibacter smithii, Which Is Associated with Higher Methane Production

Ghoshal U, Shukla R, Srivastava D, Ghoshal UC

BACKGROUND/AIMS: Because Methanobrevibacter smithii produces methane, delaying gut transit, we evaluated M. smithii loads in irritable bowel syndrome (IBS) patients and healthy controls (HC). METHODS: Quantitative real-time polymerase chain reaction for...
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Relationship Between Intestinal Gas and the Development of Right Colonic Diverticula

Jang SI, Kim JH, Youn YH, Park H, Lee SI, Conklin JL

  • KMID: 2204238
  • J Neurogastroenterol Motil.
  • 2010 Oct;16(4):418-423.
BACKGROUNDS/AIMS: High intraluminal pressure has been reported to cause left colonic diverticula. However, the pathophysiology of right colonic diverticula is still unclear. Methane gas has been reported to delay small...
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Influencing Factors on Lactulose Breath Test Results

Kim JW, Park SY, Chung JO, Cho HA, Kim DH, Yoon JH, Park CH, Kim HS, Choi SK, Rew JS

BACKGROUND/AIMS: This study aimed to identify the demographic and clinical factors associated with positive breath-test results and to assess the relationship between hydrogen and methane production in patients with suspected...
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Small Intestinal Bacterial Overgrowth

Kim SE

Small intestinal bacterial overgrowth (SIBO) syndrome is characterized by an imbalance of a complex microbiome in the gut. The underlying factors include anatomic abnormalities, (small intestinal obstruction, diverticular disease, fistulas,...
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Is Long-term Ambient Air Pollutant Exposure a Risk Factor for Irritable Bowel Syndrome in Children? A 12-year Longitudinal Cohort Study

Tan TK, Saps M, Lin CL, Wei CC

  • KMID: 2449096
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):241-249.
  • doi: 10.5056/jnm18135
BACKGROUND/AIMS: Recent studies suggest that air pollution may play a role in gastrointestinal disorders. However, the effect of long-term exposure to air pollution on childhood irritable bowel syndrome (IBS) is...
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Climate change and human health

Hong SJ, Seo JH

Climactic changes, especially global warming, are potentially the largest global threat to human health and the source of the greatest number of cases of disease. If current emissions and land...
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Comparison of Single-Breath and Intra-Breath Method inMeasuring Diffusing Capacity for Carbon Monoxide of the Lung

Lee JH, Chung HS, Shim YS

  • KMID: 2317938
  • Tuberc Respir Dis.
  • 1995 Aug;42(4):555-568.
BACKGROUND: It is most physiologic to measure the diffusing capacity of the lung by using oxygen, but it is so difficult to measure partial pressure of oxygen in the capillary...
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Positive Glucose Breath Tests in Patients with Hysterectomy, Gastrectomy, and Cholecystectomy

Kim DB, Paik CN, Kim YJ, Lee JM, Jun KH, Chung WC, Lee KM, Yang JM, Choi MG

BACKGROUND/AIMS: This study aimed to investigate the prevalence and characteristics of small intestinal bacterial overgrowth (SIBO) in patients undergoing abdominal surgeries, such as gastrectomy, cholecystectomy, and hysterectomy. METHODS: One hundred seventy-one...
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A Case of Colonic Pseudoobstruction Related to Bacterial Overgrowth Due to a Sigmoidocecal Fistula

Chung KM, Lim SU, Hong HJ, Park SY, Park CH, Kim HS, Choi SK, Rew JS

Colocolic fistulas are usually a complication of an inflammatory or neoplastic process. Development of these abnormal bowel communications may lead to bacterial overgrowth. We report on a 71-year-old man with...
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In vitro Sun Protection Factors (SPFs) of Sunscreen and Skin Irritability

Kim SJ, Lee DS, Won YH, Kim JW, Han ES, Lee SH

  • KMID: 2302850
  • Korean J Dermatol.
  • 2004 Aug;42(8):964-975.
BACKGROUND: Use of suncreen is strongly recommended to prevent the harmful effect by ultraviolet (UV) ray, and new diverse synthetic chemicals have been screened and put forward as effective UV...
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