- Effects of Topiramate on the Brain Cell Energy Metabolism in the Early Phase of Experimental Escherichia coli Meningitis
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Choi CW, Hwang JH, Lee KH, Chang YS, Park WS, Lee M
- KMID: 2099090
- J Korean Soc Neonatol.
- 2005 May;12(1):42-48.
PURPOSE: Topiramate is a novel antiepileptic drug, and is known to act as a glutamate receptor antagonist. Excitotoxicity by glutamate is also advocated as an arm of brain injury in... -
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- Effects of Hypertonic (7%) Saline on Brain Injury in Experimental Escherichia coli Meningitis
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Choi CW, Hwang JH, Chang YS, Park WS, Kim BI, Choi JH, Lee M
- KMID: 1781774
- J Korean Med Sci.
- 2005 Oct;20(5):870-876.
- doi: 10.3346/jkms.2005.20.5.870
We sought to know whether hypertonic (7%) saline (HTS) attenuates brain injury by improving cerebral perfusion pressure (CPP) and down-modulating acute inflammatory responses in experimental bacterial meningitis in the newborn... -
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- Effects of MK-801 (dizocilpine) on Brain Cell Membrane Function and Energy Metabolism in Experimental Escherichia coli Meningitis in the Newborn Piglet
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Ko SY, Shim JW, Kim SS, Kim MJ, Chang YS, Park WS, Shin SM, Lee MH
- KMID: 2157628
- J Korean Med Sci.
- 2003 Apr;18(2):236-241.
- doi: 10.3346/jkms.2003.18.2.236
We evaluated the efficacy of non-competitive N-methyl-D-aspartate receptor antagonist MK-801 (dizocilpine) as an adjuvant therapy in experimental neonal bacterial meningitis. Meningitis was induced by injecting 10(6) colony forming units of... -
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- Effects of Dopamine Infusion on Cerebral Blood Flow, Brain Cell Membrane Function and Energy Metabolism in Experimental Escherichia coli Meningitis in the Newborn Piglet
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Park WS, Chang YS, Shim JW, Kim MJ, Ko SY, Kim SS, Hwang JH, Choi CW, Lee M
- KMID: 1086746
- J Korean Med Sci.
- 2003 Dec;18(6):869-875.
- doi: 10.3346/jkms.2003.18.6.869
In the present study, we tested whether maintenance of adequate cerebral perfusion pressure (CPP) by pharmacologically preventing systemic hypotension with dopamine infusion would prevent cerebral ischemia and attenuate energy depletion... -
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