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Plasmodium vivax Drug Resistance Genes; Pvmdr1 and Pvcrt-o Polymorphisms in Relation to Chloroquine Sensitivity from a Malaria Endemic Area of Thailand

Rungsihirunrat K, Muhamad P, Chaijaroenkul W, Kuesap J, Na-Bangchang K

The aim of the study was to explore the possible molecular markers of chloroquine resistance in Plasmodium vivax isolates in Thailand. A total of 30 P. vivax isolates were collected...
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Serotonin Transporter Gene Polymorphism in Healthy Adults and Patients with Irritable Bowel Syndrome

Lee DY, Park H, Kim WH, Lee SI, Seo YJ, Choi YC

  • KMID: 1111504
  • Korean J Gastroenterol.
  • 2004 Jan;43(1):18-22.
BACKGROUND/AIMS: Serotonin is thought to be an important neurotransmitter in the pathogenesis of irritable bowel syndrome (IBS). It is reported that functional polymorphism in the promotor region of the...
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The functional domains of dopamine transporter for cocaine analog, CFT binding

Lee SH, Chang MY, Jeon DJ, Oh DY, Son H, Lee CH, Lee YS, Lee YS

  • KMID: 1093603
  • Exp Mol Med.
  • 2002 Mar;34(1):90-94.
Cocaine analogue, CFT (2beta-carbomethoxy-3beta-(4-fluorophenyl) tropane) binding to dopamine transporter (DAT) in different species is quite heterogeneous. CFT is scarcely detected in bovine DAT whereas it is conspicuous in humans. To...
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Serotonin Transporter and COMT Polymorphisms as Independent Predictors of Health-related Quality of Life in Patients with Panic Disorder

Kang E, Choe AY, Kim B, Lee JY, Choi TK, Na HR, Lee SH

There is growing evidence of poor health-related quality of life (HRQOL) in patients with panic disorder (PD). However, little is known about the factors affecting HRQOL in patients with PD....
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Serotonin transporter mRNA expression in the dorsal raphe nucleus of a tumor bearing mouse

Jahng JW, Choi SH, Cha MJ, Kim NY, Hwang SJ, Lee JH

  • KMID: 1033103
  • Exp Mol Med.
  • 2005 Feb;37(1):65-69.
This study was conducted to determine if an oral squamous cell carcinoma alters mRNA expression of serotonin transporter (5-HTT) in the central nervous system. KB cell line derived from a...
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Lack of Association between Polymorphisms of the Dopamine Receptor D4 and Dopamine Transporter Genes and Personality Traits in a Korean Population

Kim SJ, Kim YS, Kim CH, Lee HS

Human personality traits have a considerable genetic component. Cloninger et al. were the first to postulate that certain personality traits, such as novelty seeking, are related to the dopamine neurotransmitter...
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X-Linked Spondyloepiphyseal Dysplasia Tarda: Identification of a TRAPPC2 Mutation in a Korean Pedigree

Ryu H, Park J, Chae H, Kim M, Kim Y, Ok IY

Spondyloepiphyseal dysplasia (SED) comprises a heterogeneous group of skeletal dysplasias that primarily affect the epiphyses and vertebral bodies. Patients affected by SED usually exhibit short stature and experience early development...
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Serotonin Transporter Gene Polymorphisms and Chronic Illness of Depression

Myung W, Lim SW, Kim J, Lee Y, Song J, Chang KW, Kim DK

Clinical course of depression is variable. The serotonin transporter gene is one of the most studied genes for depression. We examined the association of serotonin transporter gene polymorphisms with chronicity...
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Dopamine Transporter Genotype Influences the Attention Deficit in Korean Boys with ADHD

Oh KS, Shin DW, Oh GT, Noh KS

  • KMID: 2428344
  • Yonsei Med J.
  • 2003 Oct;44(5):787-792.
Attention appears to be inheritable, stable and influenced by genetic factors. The use of the Continuous Performance Test (CPT), as an endophenotypic measure, is valuable for genetic studies because it...
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No Association between 5-HTTLPR and Harm Avoidance in Korean College Students

Joo YH, Oh HB, Kim B, Jung SH, Chung JK, Hong JP, Kim CY

There have been numerous studies on the association between 5-HTTLPR (polymorphisms in the promoter region of the serotonin transporter gene) and anxietyrelated personality traits, with conflicting results. In this study,...
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