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Relaxin Modulates the Expression of MMPs and TIMPs in Fibroblasts of Patients with Carpal Tunnel Syndrome

Kang YM, Lee HM, Moon SH, Kang H, Choi YR

PURPOSE: The aim of this study was to investigate the anti-fibrotic effect of relaxin in subsynovial fibroblasts activated by transforming growth factor beta (TGF-β). MATERIALS AND METHODS: To test the anti-fibrotic...
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The Increased Expression of Matrix Metalloproteinases Associated with Elastin Degradation and Fibrosis of the Ligamentum Flavum in Patients with Lumbar Spinal Stenosis

Park JB, Kong CG, Suhl KH, Chang ED, Riew KD

BACKGROUND: One of the characteristics of spinal stenosis is elastin degradation and fibrosis of the extracellular matrix of the ligamentum flavum. However, there have been no investigations to determine which...
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The Expression of Matrix Metalloproteinases (MMPs), Tissue Inhibitor of Metalloproteinases (TIMPs) and Angiogenesis in Relation to the Depth of Tumor Invasion and Lymph Node Metastasis in Submucosally Invasive Colorectal Carcinoma

Jung SA, Yang SK, Kim JS, Shim KN, Im SA, Myung SJ, Jung HY, Yu CS, Kim JC, Hong WS, Kim JH, Min YI

  • KMID: 772787
  • Korean J Gastroenterol.
  • 2005 Jun;45(6):401-408.
BACKGROUND/AIMS: Lymph node (LN) metastasis occurs in approximately 10% of patients with submucosally invasive colorectal carcinoma. This study was performed to determine the role of matrix metalloproteinases (MMPs), tissue...
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Upregulation of extracellular matrix metalloproteinase inducer (EMMPRIN) and gelatinases in human atherosclerosis infected with Chlamydia pneumoniae: The potential role of Chlamydia pneumoniae infection in the progression of atherosclerosis

Choi EY, Kim DS, Hong BK, Kwon HM, Song YG, Byun KH, Park HY, Whang KC, Kim HS

  • KMID: 1121092
  • Exp Mol Med.
  • 2002 Dec;34(6):391-400.
Chlamydia pneumoniae infection implicated as an important etiologic factor of atherosclerosis, especially in coronary artery disease (CAD), was found in vitro to be associated with the induction of matrix...
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