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The Anticollagenase Effect of Serum in Alkali-burned Cornea in Rabbit

Park DH, Yoon BJ

  • KMID: 1949366
  • J Korean Ophthalmol Soc.
  • 1988 Aug;29(4):511-515.
The possible role of collagenase in the development of corneal ulcers has been intensively studied and collagenase inhibitors have been successfully used to control some corneal ulcers. They are cysteine,...
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Alkali Burns of the Cornea

Youn DH

  • KMID: 1948546
  • J Korean Ophthalmol Soc.
  • 1972 Jun;13(2):59-62.
1. Alkali burns of rabbit corneas were produced by 5.0 N NaOH swabbing the cornea and surrounding sclera. 2. Collagenolytic activity of alkali burned corneas, and the effectiveness of collagenase...
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Matrix Metalloproteinase Inhibitors Attenuate Neuroinflammation Following Focal Cerebral Ischemia in Mice

Park CH, Shin TK, Lee HY, Kim SJ, Lee WS

The aim of this study was to investigate whether matrix metalloproteinase (MMP) inhibitors attenuate neuroinflammation in an ischemic brain following photothrombotic cortical ischemia in mice. Male C57BL/6 mice were anesthetized,...
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Comparison of the Effects of Matrix Metalloproteinase Inhibitors on TNF-alpha Release from Activated Microglia and TNF-alpha Converting Enzyme Activity

Lee EJ, Moon PG, Baek MC, Kim HS

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that regulate cell-matrix composition and are also involved in processing various bioactive molecules such as cell-surface receptors, chemokines, and cytokines. Our group recently reported...
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SKI306X inhibition of glycosaminoglycan degradation in human cartilage involves down-regulation of cytokine-induced catabolic genes

Choi CH, Kim TH, Sung YK, Choi CB, Na YI, Yoo H, Jun JB

BACKGROUND/AIMS: SKI306X, a mixed extract of three herbs, Clematis mandshurica (CM), Prunella vulgaris (PV), and Trichosanthes kirilowii (TK), is chondroprotective in animal models of osteoarthritis (OA). The objectives of this...
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The Effect of the Genistein on the Proliferation of HT1080 and Expression of Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) mRNA

Kang JH, Myoung H, Kim MJ

  • KMID: 2328354
  • J Korean Assoc Oral Maxillofac Surg.
  • 2001 Aug;27(4):314-320.
Matrix metalloproteinases have long been viewed as ideal candidates for proteinases that enables tumor cells to permeated basement membrane defenses and invade surrounding tissue. There is growing evidence that the...
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Clinical Effects of Shark Cartilage Extracts on Erythematotelangiectatic Rosacea Patients

Han TY, Kim BJ, Kim MN, Huh CH, Rho NK, Kim SH, Hong HK, Choi YS, Jo YC

  • KMID: 2014466
  • Korean J Dermatol.
  • 2007 Dec;45(12):1253-1257.
BACKGROUND: Persistent facial telangiectasia, erythema and flushing are the major cosmetic problems in patients with rosacea. However various therapeutic treatments for rosacea papules and pustules are not effective in reducing...
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Effects of Topical Intranasal Doxycycline Treatment in the Rat Allergic Rhinitis Model

Avincsal M, Ozbal S, Ikiz AO, Pekcetin C, Guneri EA

  • KMID: 2278383
  • Clin Exp Otorhinolaryngol.
  • 2014 Jun;7(2):106-111.
OBJECTIVES: Allergic rhinitis (AR) is a chronic upper respiratory tract disease that inflames the mucous membranes of the nose and occurs when circulating inflammatory cells including eosinophils and basophils migrate...
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Efficacy of horse chestnut leaf extract ALH-L1005 as a matrix metalloproteinase inhibitor in ligature-induced periodontitis in canine model

Kim SE, Kim TH, Park SA, Kim WT, Park YW, Ahn JS, Jeong M, Kim MY, Seo K

Matrix metalloproteinases (MMPs) are the main proteinases associated with periodontal tissue destruction and remodeling. Therefore, inhibition of host-derived MMPs has a key role in the prevention and reduction of periodontitis...
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Recent Trend in The Treatment of Non-Small Cell Lung Cancer Non-small cell lung cancer

Lee KY

  • KMID: 2200222
  • J Lung Cancer.
  • 2002 Dec;1(1):1-8.
(NSCLC) accounts for more than 80% of all lung cancer cases. Even though surgery plays a key role in the curative management of NSCLC, especially the stage I or II...
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Experimental Studies on the Therapeutic Effects of Soft Contact Lens Soaked in Collagenase Inhibitor Solutions

Hong C

  • KMID: 1659466
  • J Korean Ophthalmol Soc.
  • 1977 Jun;18(2):151-162.
Many investigations have been performed to evaluate the therapeutic usefulness of hydrophilic soft contact lenses for the corneal diseases. In this study the author undertook to determine the uptake and...
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