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Blackwater Fever Followed by Severe Falciparum Malaria in a Child

Yang SI, Choe YJ, Lee HJ, Choi EH

Blackwater fever is a serious clinical syndrome manifested by acute intravascular hemolysis, fever, and the passage of black or red urine, which is classically associated with falciparum malaria and irregular...
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Whole Mitochondrial Genome Sequence of an Indian Plasmodium falciparum Field Isolate

Tyagi S, Pande V, Das A

Mitochondrial genome sequence of malaria parasites has served as a potential marker for inferring evolutionary history of the Plasmodium genus. In Plasmodium falciparum, the mitochondrial genome sequences from around the...
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Predictive score of uncomplicated falciparum malaria patients turning to severe malaria

Tangpukdee N, Krudsood S, Thanachartwet V, Duangdee C, Paksala S, Chonsawat , Srivilairit S, Looareesuwan S, Wilairatana P

In acute uncomplicated falciparum malaria, there is a continuum from mild to severe malaria. However, no mathematical system is available to predict uncomplicated falciparum malaria patients turning to severe malaria....
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Possible Role of Heme Oxygenase-1 and Prostaglandins in the Pathogenesis of Cerebral Malaria: Heme Oxygenase-1 Induction by Prostaglandin D2 and Metabolite by a Human Astrocyte Cell Line

Kuesap J, Na-Bangchang K

Astrocytes are the most abundant cells in the central nervous system that play roles in maintaining the blood-brain-barrier and in neural injury, including cerebral malaria, a severe complication of Plasmodium...
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Coexistence of Malaria and Thalassemia in Malaria Endemic Areas of Thailand

Kuesap J, Chaijaroenkul W, Rungsihirunrat K, Pongjantharasatien K, Na-Bangchang K

Hemoglobinopathy and malaria are commonly found worldwide particularly in malaria endemic areas. Thalassemia, the alteration of globin chain synthesis, has been reported to confer resistance against malaria. The prevalence of...
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Peripheral gangrene in patients with severe falciparum malaria: report of 3 cases

Thanachartwet V, Krudsood S, Wilairatana P, Phumratanaprapin W, Silachamroon U, Looareesuwan S

Peripheral gangrene, characterized by distal ischemia of the extremities, is a rare complication in patients with falciparum malaria. Patients with this complication have generally undergone early amputation of the affected...
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Allelic Diversity and Geographical Distribution of the Gene Encoding Plasmodium falciparum Merozoite Surface Protein-3 in Thailand

Sawaswong , Simpalipan P, Siripoon N, Harnyuttanakorn P, Pattaradilokrat S

Merozoite surface proteins (MSPs) of malaria parasites play critical roles during the erythrocyte invasion and so are potential candidates for malaria vaccine development. However, because MSPs are often under strong...
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Prevalence and Clinical Manifestations of Malaria in Aligarh, India

Asma UE, Taufiq F, Khan W

Malaria is one of the most widespread infectious diseases of tropical countries with an estimated 207 million cases globally. In India, there are endemic pockets of this disease, including Aligarh....
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A Locally Acquired Falciparum Malaria via Nosocomial Transmission in Korea

Kim JY, Kim JS, Park MH, Kang YA, Kwon JW, Cho SH, Lee BC, Kim TS, Lee JK

A 57-year old man who was admitted to an emergency room of a tertiary hospital with hemoptysis developed malarial fever 19 days later and then died from severe falciparum malaria...
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Two Cases of Severe Plasmodium falciparum Malaria Complicated with Acute Respiratory Distress Syndrome

Choi SM, Lee YJ, Park SH, Koh MB, Kim SI, Kim YR, Kim YK, Kang MW

  • KMID: 2147889
  • Korean J Infect Dis.
  • 2001 Oct;33(5):354-359.
Malaria remains one of the most important infectious diseases in the world. For those not immuned to malaria, delayed diagnosis and treatment have been associated with an increase in morbidity...
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Evolution of Genetic Polymorphisms of Plasmodium falciparum Merozoite Surface Protein (PfMSP) in Thailand

Kuesap J, Chaijaroenkul W, Ketprathum K, Tattiyapong P, Na-Bangchang K

Plasmodium falciparum malaria is a major public health problem in Thailand due to the emergence of multidrug resistance. The understanding of genetic diversity of malaria parasites is essential for developing...
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Genetic diversity in merozoite surface protein (MSP)-1 and MSP-2 genes of Plasmodium falciparum in a major endemic region of Iran

Heidari A, Keshavarz , Rokni MB, Jelinek T

Merozoite surface protein-1 (MSP-1) and merozoite surface protein-2 (MSP-2) were used to develop vaccines and to investigate the genetic diversity in Plasmodium falciparum malaria in Iran. Nested polymerase chain reaction...
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Potential Interaction of Plasmodium falciparum Hsp60 and Calpain

Yeo SJ, Liu DX, Park H

After invasion of red blood cells, malaria matures within the cell by degrading hemoglobin avidly. For enormous protein breakdown in trophozoite stage, many efficient and ordered proteolysis networks have been...
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Delayed Diagnosis of Falciparum Malaria with Acute Kidney Injury

Choi IH, Hwang PH, Choi SI, Lee DY, Kim MS

Prompt malaria diagnosis is crucial so antimalarial drugs and supportive care can then be rapidly initiated. A 15-year-old boy who had traveled to Africa (South Africa, Kenya, and Nigeria between...
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Gametocyte Clearance in Uncomplicated and Severe Plasmodium falciparum Malaria after Artesunate-Mefloquine Treatment in Thailand

Tangpukdee N, Krudsood S, Srivilairit S, Phophak N, Chonsawat , Yanpanich , Kano S, Wilairatana P

Artemisinin-based combination therapy (ACT) is currently promoted as a strategy for treating both uncomplicated and severe falciparum malaria, targeting asexual blood-stage Plasmodium falciparum parasites. However, the effect of ACT on...
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Allelic Diversity of MSP1 Gene in Plasmodium falciparum from Rural and Urban Areas of Gabon

Mawili-Mboumba DP, Mbondoukwe N, Adande E, Bouyou-Akotet MK

The present study determined and compared the genetic diversity of Plasmodium falciparum strains infecting children living in 2 areas from Gabon with different malaria endemicity. Blood samples were collected from...
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Effect of Farnesyltransferase Inhibitor R115777 on Mitochondria of Plasmodium falciparum

Ha YR, Hwang BG, Hong Y, Yang HW, Lee SJ

The parasite Plasmodium falciparum causes severe malaria and is the most dangerous to humans. However, it exhibits resistance to their drugs. Farnesyltransferase has been identified in pathogenic protozoa of the...
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Nested-PCR and a New ELISA-Based NovaLisa Test Kit for Malaria Diagnosis in an Endemic Area of Thailand

Thongdee P, Chaijaroenkul W, Kuesap J, Na-Bangchang K

Microscopy is considered as the gold standard for malaria diagnosis although its wide application is limited by the requirement of highly experienced microscopists. PCR and serological tests provide efficient diagnostic...
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Evaluation of the Accuracy of the EasyTest(TM) Malaria Pf/Pan Ag, a Rapid Diagnostic Test, in Uganda

Chong CK, Cho PY, Na BK, Ahn SK, Kim JS, Lee JS, Lee SK, Han ET, Kim HY, Park YK, Cha SH, Kim TS

In recent years, rapid diagnostic tests (RDTs) have been widely used for malaria detection, primarily because of their simple operation, fast results, and straightforward interpretation. The Asan EasyTest(TM) Malaria Pf/Pan...
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Sensitivity of Plasmodium falciparum to Antimalarial Drugs in Hainan Island, China

Wang SQ, Wang GZ, Li YC, Meng F, Lin SG, Zhu ZH, Sun DW, He CH, Hu XM, Du JW

Pyronaridine and artesunate have been shown to be effective in falciparum malaria treatment. However, pyronaridine is rarely used in Hainan Island clinically, and artesunate is not widely used as a...
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