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Nanomedicines for Therapy of Bladder Cancer

Song C, Jang SJ, Jeon WH, Maeng S, Tae JH, Chang IH

Bladder cancer is one of most common malignant urinary tract tumor types, and transurethral resection of nonmuscle invasive bladder cancer followed by intravesical instillation of immunochemotherapy is the standard treatment...
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Msi1-Like (MSIL) Proteins in Fungi

Yang DH, Maeng S, Bahn YS

  • KMID: 2312679
  • Mycobiology.
  • 2013 Mar;41(1):1-12.
Msi1-like (MSIL) proteins, which are eukaryote-specific and contain a series of WD40 repeats, have pleiotropic roles in chromatin assembly, DNA damage repair, and regulation of nutrient/stress-sensing signaling pathways. In the...
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Central precocious puberty with hypothalamic hamartoma: the first case reports of 2 siblings with different phenotypes of Seckel syndrome 5

Park J, Jeon M, Maeng S, Kwon DK, Kim S, Lee JE

Hypothalamic hamartomas (HHs) are nonneoplastic mass lesions located in the hypothalamus that can cause central precocious puberty (CPP) and/or gelastic seizures. Seckel syndrome 5 (OMIM210600, SCKL5) is a rare autosomal...
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Animal Models for Bone Metastatic Prostate Cancer

Jeon WH, Song C, Jang SJ, Maeng S, Chang IH, Tae JH

Metastatic disease is a main cause of mortality in prostate cancer and remains to be uncurable despite emerging new treatment agents. Development of novel treatment agents are confined within the...
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Effect of bromocriptine on 6-hydroxydopamine-induced lipid peroxidation and cytotoxicity in vitro and in vivo

Kim YS, Maeng S, Park CW

  • KMID: 2071536
  • Korean J Physiol Pharmacol.
  • 1998 Oct;2(5):565-572.
The present study was to evaluate the protective effects of bromocriptine, which is known as D2 dopamine receptor agonist and used for the treatment of patients with Parkinson's disease (PD), on 6-hydroxydopamine (6-OHDA)-induced...
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Mrakia terrae sp. nov. and Mrakia soli sp. nov., Two Novel Basidiomycetous Yeast Species Isolated from Soil in Korea

Park Y, Maeng S, Oh J, Sung GH, Srinivasan S

Three strains, YP416 T , YP421 T, and Y422, were isolated from soil samples in Pocheon City, Gyeonggi province, South Korea. The strains belong to two novel yeast species in...
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Ceramide is Involved in MPP+ -induced Cytotoxicity in Human Neuroblastoma Cells

Nam EJ, Lee HS, Lee YJ, Joo WS, Maeng S, Im HI, Park CW, Kim YS

  • KMID: 1615193
  • Korean J Physiol Pharmacol.
  • 2002 Dec;6(6):281-286.
To understand the cytotoxic mechanism of MPP+, we examined the involvement of ceramide in MPP+ -induced cytotoxicity to human neuroblastoma SH-SY5Y cells. When SH-SY5Y cells were exposed to MPP+, MPP+...
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The Difference in the Quality of Life of Korean Children With Attention-Deficit/Hyperactivity Disorder Between Before and After COVID-19

Lee JH, Maeng S, Lee JS, Bae JN, Kim WH, Kim H

  • KMID: 2533347
  • J Korean Acad Child Adolesc Psychiatry.
  • 2022 Oct;33(4):113-121.
  • doi: 10.5765/jkacap.220019
Objectives: This study aimed to compare the quality of life (QoL) of children with attention-deficit/hyperactivity disorder (ADHD) before and during coronavirus disease-2019 (COVID-19) and to examine how their QoL is...
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Functional Characterization of cAMP-Regulated Gene, CAR1, in Cryptococcus neoformans

Jung KW, Maeng S, Bahn YS

  • KMID: 2312560
  • Mycobiology.
  • 2010 Mar;38(1):26-32.
The cyclic AMP (cAMP) pathway plays a major role in growth, sexual differentiation, and virulence factor synthesis of pathogenic fungi. In Cryptococcus neoformans, perturbation of the cAMP pathway, such as...
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The Influence of Nurses' Communication Competency, Critical Thinking Disposition, and Perception of Patient Safety Culture on Patient Safety Competency in Armed Forces Hospitals

Yoon S, Lee T, Maeng S, Kwon Je

Purpose: This study examined the influence of nurses' communication competency, critical thinking disposition, and perception of patient safety culture on patient safety competency in armed forces hospitals. Methods: A crosssectional...
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Association between Perceived Parenting Style and Adolescents’ Attitudes toward Suicide

Choi SH, Lee SE, Lee CW, Maeng S, Son J, Kim WH, Bae JN, Lee JS, Kim H

  • KMID: 2507490
  • J Korean Acad Child Adolesc Psychiatry.
  • 2020 Oct;31(4):193-200.
  • doi: 10.5765/jkacap.200032
Objectives: Adolescent suicide, a major cause of adolescent death, is affected by various factors, including attitudes toward suicide. This study investigated the association between parenting style and adolescents’ attitudes toward suicide...
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A Comparative Analysis of Neurocognitive Function in Community- and Hospital-Based Patients With Schizophrenia

Maeng S, Kim HS, Lee TJ, Koo HJ, Kim WH

Objective The study compared differences in various neurocognitive characteristics across treatment modalities among schizophrenia patients recruited in one city between July 2020 and June 2023 who were on regular medication. Methods...
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Significant Domains of Life Satisfaction That Affect Suicidal Behavior in Adolescents

Kim JS, Choi SH, Lee SE, Lee CW, Kim WH, Bae JN, Lee JS, Maeng S, Son J, Kim H

  • KMID: 2516959
  • J Korean Acad Child Adolesc Psychiatry.
  • 2021 Jul;32(3):104-111.
  • doi: 10.5765/jkacap.210004
Objectives: Adolescent suicide is a serious national issue in Korea. Recently, life satisfaction has been recognized as a major factor related to this issue. The main purpose of this study...
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Effects of Virtual Reality-Based Cognitive Training in the Elderly with and without Mild Cognitive Impairment

Maeng S, Hong JP, Kim WH, Kim H, Cho SE, Kang JM, Na KS, Oh SH, Park JW, Bae JN, Cho SJ

Objective This study aimed to introduce a 4-week long fully immersive virtual reality-based cognitive training (VRCT) program that could be applied for both a cognitively normal elderly population and patients...
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Empty Sella Syndrome Associated with Growth Hormone Deficiency: the First Case Report of WeissKruszka Syndrome

Park J, Ha DJ, Seo GH, Maeng S, Kang SM, Kim S, Lee JE

Weiss-Kruszka syndrome (WSKA), caused by heterozygous loss-of-function variants in ZNF462 gene, is a recently described and extremely rare genetic disorder. The main phenotypes include characteristic craniofacial features, ptosis, dysgenesis of...
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Effects of pumpkin seed oil and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia

Hong H, Kim CS, Maeng S

  • KMID: 2392048
  • Nutr Res Pract.
  • 2009 Dec;3(4):323-327.
This study was to investigate the role of complementary and alternative medicine in the prevention and treatment of benign prostatic hyperplasia. For this purpose, a randomized, double-blind, placebo-controlled trial was...
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Radix Polygalae Extract Attenuates PTSD-like Symptoms in a Mouse Model of Single Prolonged Stress and Conditioned Fear Possibly by Reversing BAG1

Shin JY, Shin JW, Ha SK, Kim Y, Swanberg K, Lee S, Kim TW, Maeng S

Radix Polygalae (RP) has been used to relieve psychological stress in traditional oriental medicine. Recently, cell protective, antiamnestic and antidepressant-like effects were disclosed but the possible application of RP to...
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Involvement of Oxidative Stress and Poly (ADP-ribose) Polymerase Activation in 3-Nitropropionic Acid-induced Cytotoxicity in Human Neuroblastoma Cells

Nam E, Lee YJ, Oh YA, Jung JA, Im HI, Koh SE, Maeng S, Joo WS, Kim YS

  • KMID: 1607517
  • Korean J Physiol Pharmacol.
  • 2003 Dec;7(6):325-331.
3-Nitropropionic acid (3-NP) inhibits electron transport in mitochondria, leading to a metabolic failure. In order to elucidate the mechanism underlying this toxicity, we examined a few biochemical changes possibly involved...
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Efficacy of recombinant Bacillus Calmette-Guérin containing dltA in in vivo three-dimensional bio-printed bladder cancer-on-a-chip and ex vivo orthotopic mouse model

Choi J, Jung TY, Kim JH, Maeng S, Kang SJ, Kim M, Choi YW, Choi SY, Kim SH, Chang IH

Purpose: We investigated the efficacy and optimal dosage of recombinant Bacillus Calmette-Guérin-dltA (rBCG-dltA) in a high-th roughput 3D bio-printed bladder cancer-on-a-chip (BCOC) and orthotopic bladder cancer mouse model. Materials and Methods:...
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Antidepressant-like Effects of p-Coumaric Acid on LPS-induced Depressive and Inflammatory Changes in Rats

Lee S, Kim HB, Hwang ES, Kim ES, Kim SS, Jeon TD, Song MC, Lee JS, Chung MC, Maeng S, Park JH

Depression causes mental and physical changes which affect quality of life. It is estimated to become the second most prevalent disease, but despite its commonness, the pathophysiology of depression remains...
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