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Macrophage colony-stimulating factor promotes the survival of osteoclast precursors by up-regulating Bcl-XL

Woo KM, Kim HM, Ko JS

  • KMID: 755205
  • Exp Mol Med.
  • 2002 Nov;34(5):340-346.
Macrophage colony-stimulating factor (M-CSF) is known as one of the factors essential for osteoclast development. In the present study, we examined effects of M-CSF on the apoptotic pathway of osteoclast...
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Granulocyte Macrophage Colony-Stimulating Factor May Modulate the Post-transcription Pathway of Interleukin-6 Expression in Prostate Carcinoma Cells

Kim TH, Oh SY, Kim YS, Lee MK, Kim HS, Myung SC

Interleukin-6 (IL-6) can stimulate a variety of tumors including prostatic carcinoma. Research has recently shown that IL-6 may act to stimulate the progression of prostatic cancer. To date, little research...
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Mesenchymal stem cells reciprocally regulate the M1/M2 balance in mouse bone marrow-derived macrophages

Cho DI, Kim MR, Jeong HY, Jeong HC, Jeong MH, Yoon SH, Kim YS, Ahn Y

Mesenchymal stem cells (MSCs) have been widely studied for their applications in stem cell-based regeneration. During myocardial infarction (MI), infiltrated macrophages have pivotal roles in inflammation, angiogenesis and cardiac remodeling....
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Differential responses of CD34-positive acute myelogenous leukemic blasts to the costimulating effects of stem cell factor with GM-CSF and/or IL-3

Min YH, Lee ST, Lee BK, Chong SY, Lee S, Hahn JS, Ko YW

Stem cell factor (SCF), a c-kit ligand, has a preferential effect on the proliferation of several classes of immature hematopoietic progenitor cells in combination with GM-CSF or IL-3. To analyze...
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Synergistic activation of p70S6 kinase associated with stem cell factor in MO7e cells

Lee Y, Broxmeyer , Mantel C, Kwon HJ, Kim JW, Kim JS, Kwon D, Choe IS

  • KMID: 1094704
  • Exp Mol Med.
  • 2003 Jun;35(3):222-226.
Stem cell factor (SCF) is an early-acting cytokine inducing proliferative synergy with other cytokines in hematopoietic cells. We earlier showed that p21 was synergistically induced in SCF synergy and the...
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